ChemicalBook > CAS DataBase List > Bis-PEG9-PFP ester

Bis-PEG9-PFP ester

Product Name
Bis-PEG9-PFP ester
CAS No.
1334170-00-1
Chemical Name
Bis-PEG9-PFP ester
Synonyms
Bis-dPEG®Bis-PEG9-PFP ester;Bis-dPEG(R)9-PFP ester;Bis-dPEG(R)13-PFP ester;9-PFP ester;Bis-dPEG?9-PFP ester;Bis-dPEG?13-PFP ester;alpha,omega-Bis(pentafluorphenyl propionate) dodeca(ethylene glycol);bis(2,3,4,5,6-pentafluorophenyl) 4,7,10,13,16,19,22,25,28-nonaoxahentriacontanedioate;4,7,10,13,16,19,22,25,28-Nonaoxahentriacontanedioic acid, 1,31-bis(2,3,4,5,6-pentafluorophenyl) ester
CBNumber
CB73062420
Molecular Formula
C34H40F10O13
Formula Weight
846.66
MOL File
1334170-00-1.mol
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Bis-PEG9-PFP ester Property

storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM
form 
solid or viscous liquid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
QBD10984
Product name
Bis-dPEG®13-PFP ester
Packaging
100MG
Price
$364
Updated
2025/07/31
Sigma-Aldrich
Product number
QBD10984
Product name
Bis-dPEG®13-PFP ester
Packaging
1000MG
Price
$1660
Updated
2025/07/31
Sigma-Aldrich
Product number
QBD10983
Product name
Bis-dPEG®9-PFP ester
Packaging
100MG
Price
$363
Updated
2025/07/31
Sigma-Aldrich
Product number
QBD10983
Product name
Bis-dPEG®9-PFP ester
Packaging
1000MG
Price
$1660
Updated
2025/07/31
TRC
Product number
B592835
Product name
Bis-PEG13-PFPEster
Packaging
50mg
Price
$330
Updated
2021/12/16
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Bis-PEG9-PFP ester Chemical Properties,Usage,Production

Description

Bis-PEG9-PFP ester is a PEG linker with two activated PFP ester moieties. PFP esters can react with amine groups to form amide bonds. They are also less susceptible to undergo hydrolysis compared to other amine reactive groups. The hydrophilic PEG linker increase the water solubility of the compond in aqueous media.

Uses

Bis-PEG9-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bis-PEG9-PFP ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis-PEG9-PFP ester Suppliers

Sigma-Aldrich
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1334170-00-1, Bis-PEG9-PFP esterRelated Search:


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