N-methyl-N-(t-Boc)-PEG4-acid

Product Name: N-methyl-N-(t-Boc)-PEG4-acid
CAS No.: 1260431-01-3
Chemical Name: N-methyl-N-(t-Boc)-PEG4-acid
Synonyms: Boc-MeN-PEG4-CH2CH2COOH;N-methyl-N-(t-Boc)-PEG-COOH;N-methyl-N-( Boc)-PEG4-acid;N-methyl-N-(t-Boc)-PEG4-acid;N-methyl-N-(t-Boc)-PEG4-COOH;2,2,5-Trimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid;5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester;Boc-MeN-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester
CBNumber: CB73062596
Molecular Formula: C17H33NO8
Formula Weight: 379.45
MOL File: 1260431-01-3.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B665208
Product name: N-methyl-N-(t-Boc)-PEG4-acid
Packaging: 10mg
Price: $90
Updated: 2021/12/16

BroadPharm

Product number: BP-22766
Product name: N-methyl-N-(t-Boc)-PEG4-acid
Purity: 98%
Packaging: 250mg
Price: $360
Updated: 2021/12/16

BroadPharm

Product number: BP-22766
Product name: N-methyl-N-(t-Boc)-PEG4-acid
Purity: 98%
Packaging: 500mg
Price: $650
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1675
Product name: N-Methyl-N-(t-Boc)-PEG4-acid
Packaging: 250mg
Price: $701
Updated: 2021/12/16

BroadPharm

Product number: BP-22766
Product name: N-methyl-N-(t-Boc)-PEG4-acid
Purity: 98%
Packaging: 1g
Price: $950
Updated: 2021/12/16

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N-methyl-N-(t-Boc)-PEG4-acid Chemical Properties,Usage,Production

Description

N-methyl-N-(t-Boc)-PEG4-acid is a PEG linker containing a t-Boc protecting group and a terminal carboxylic acid. The t-Boc protecting group is acid lablie. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media.

Uses

N-Methyl-N-(t-Boc)-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-methyl-N-(t-Boc)-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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N-methyl-N-(t-Boc)-PEG4-acid Suppliers

China 37 United Kingdom 1 United States 2 Global 40

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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TargetMol Chemicals Inc.

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View Lastest Price from N-methyl-N-(t-Boc)-PEG4-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-Methyl-N-(t-Boc)-PEG4-Acid 1260431-01-3
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

1260431-01-3, N-methyl-N-(t-Boc)-PEG4-acidRelated Search:

N-methyl-N-(t-Boc)-PEG4-COOH

N-methyl-N-(t-Boc)-PEG4-acid

N-methyl-N-( Boc)-PEG4-acid

5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester

Boc-MeN-PEG4-CH2CH2COOH

N-methyl-N-(t-Boc)-PEG-COOH

Boc-MeN-PEG4-CH2CH2COOH/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester

2,2,5-Trimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid

1260431-01-3

C17H33NO8

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