Propargyl-PEG2- acrylate

Product Name: Propargyl-PEG2- acrylate
CAS No.: 52436-42-7
Chemical Name: Propargyl-PEG2- acrylate
Synonyms: Alkyne-PEG2-AC;PROPARGYL-PEG2-AC;Acrylate-PEG1-Propargyl;Propargyl-PEG1-acrylate;Propargyl-PEG2- acrylate;2-(Prop-2-yn-1-yloxy)ethyl acrylate;2-Propenoic acid, 2-(2-propyn-1-yloxy)ethyl ester
CBNumber: CB73062617
Molecular Formula: C8H10O3
Formula Weight: 154.16
MOL File: 52436-42-7.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P839778
Product name: Propargyl-PEG2-acrylate
Packaging: 1mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1712
Product name: Propargyl-PEG2- acrylate
Packaging: 100mg
Price: $486
Updated: 2021/12/16

BroadPharm

Product number: BP-21658
Product name: Propargyl-PEG2-acrylate
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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Propargyl-PEG2- acrylate Chemical Properties,Usage,Production

Uses

Propargyl-PEG1-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-acrylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Biological Activity

Propargyl-PEG1-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs; Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Propargyl-PEG2- acrylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG2- acrylate Suppliers

China 28 United Kingdom 1 United States 3 Global 32

Hunan HuaTeng Pharmaceutical Co., Ltd.,

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View Lastest Price from Propargyl-PEG2- acrylate manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG2-acrylate 52436-42-7
Price: US $0.00/mg
Min. Order: 250mg
Purity: >98.00%
Supply Ability: 250mg
Release date: 2024-03-26

52436-42-7, Propargyl-PEG2- acrylateRelated Search:

Propargyl-PEG2- acrylate

Alkyne-PEG2-AC

PROPARGYL-PEG2-AC

Propargyl-PEG1-acrylate

2-Propenoic acid, 2-(2-propyn-1-yloxy)ethyl ester

Acrylate-PEG1-Propargyl

2-(Prop-2-yn-1-yloxy)ethyl acrylate

52436-42-7

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