Treatment of Allergy Safety
ChemicalBook > CAS DataBase List > 2-(3-(4-hydroxyphenyl)propanamido)benzoic acid

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid

Treatment of Allergy Safety
Product Name
2-(3-(4-hydroxyphenyl)propanamido)benzoic acid
CAS No.
697235-49-7
Chemical Name
2-(3-(4-hydroxyphenyl)propanamido)benzoic acid
Synonyms
HYDROXYPHENYL PROPAMIDOBENZOIC ACID;Dihydrogen alkaloid;NanoCalmin;NanoCalmin 5%;Dihydroavenatine;Dihydrooat alkaloid;Avena sativa alkaloi;Dihydrooat alkaloids;Dihydroavenanthramide;Dihydrobiooat alkaloid
CBNumber
CB73070520
Molecular Formula
C16H15NO4
Formula Weight
285.29
MOL File
697235-49-7.mol
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2-(3-(4-hydroxyphenyl)propanamido)benzoic acid Property

Boiling point:
590.0±40.0 °C(Predicted)
Density 
1.354±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 20℃
pka
3.47±0.10(Predicted)
Water Solubility 
86.5mg/L at 20℃
InChI
InChI=1S/C16H15NO4/c18-12-8-5-11(6-9-12)7-10-15(19)17-14-4-2-1-3-13(14)16(20)21/h1-6,8-9,18H,7,10H2,(H,17,19)(H,20,21)
InChIKey
DLFOKZQWYFNKCL-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=CC=C1NC(=O)CCC1=CC=C(O)C=C1
LogP
3.05 at 20℃
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Hazard and Precautionary Statements (GHS)

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2-(3-(4-hydroxyphenyl)propanamido)benzoic acid Chemical Properties,Usage,Production

Treatment of Allergy

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid, also called hydroxyphenyl propamidobenzoic acid, is a good anti-irritant ingredient effectively reduces skin itching. It is derived from the active ingredient of oat (Avena Sativa), also known as dihydro oat acyl anthranilic acid, oat avenanthramides or oat amide. Oat amide is an antioxidant substance unique in oat and has the highest content in the aleurone layer. Oat amide is used in bath product additives to relieve dry skin symptoms and skin itching.
2-(3-(4-hydroxyphenyl) propanamido) benzoic acid is a kind of efficient ingredients in anti-irritant and inflammation reduction. It is an antihistamine which can effectively reduces itching and redness. Moreover, this drug has a wide range of applications, such as a remarkable effect on skin care, hair care, body care and scalp care.

Safety

Some experts have studied the functional role of hydroxyphenyl propamidobenzoic acid in animals. The mice were fed in 2 groups. One is normal and the other added hydroxyphenyl propamidobenzoic acid at a dose of 0.1 g/kg, the purpose of which is to see the ability of this substance to regulate the tissue oxidation and antioxidant balance in the mice. In addition, 50 days after feeding the mice, the two groups of mice were divided into the exercise group and the non-exercise group to study the effect of hydroxyphenyl propamidobenzoic acid on the oxidation induced by exercise in the internal organs of mice.

Uses

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid can be used as a raw material for cosmetics, It works as a skin soothing agent thanks to its triple anti-irritant benefits: reduces redness, inflammation and itch PLUS has anti-oxidant efficacy.

Flammability and Explosibility

Non flammable

2-(3-(4-hydroxyphenyl)propanamido)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-(3-(4-hydroxyphenyl)propanamido)benzoic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Dihydrogen alkaloid 697235-49-7
Price
US $80.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-(3-(4-hydroxyphenyl)propanamido)benzoic acid 697235-49-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2021-07-28
S&Y Biochem Co.,Ltd
Product
2-(3-(4-hydroxyphenyl)propanamido)benzoic acid 697235-49-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99
Supply Ability
1000
Release date
2024-09-23

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