ChemicalBook > CAS DataBase List > (1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID

(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID

Product Name
(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
CAS No.
582314-48-5
Chemical Name
(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
Synonyms
CAY10443;CKERQCMQSBFFKX-INIZCTEOSA-N;(S)-INDAN-1-YL 3,4-DICHLOROBENZYLCARBAMATE;(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID;Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1S)-2,3-dihydro-1H-inden-1-yl ester (9CI)
CBNumber
CB7308552
Molecular Formula
C17H15Cl2NO2
Formula Weight
336.21
MOL File
Mol file
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(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Property

Boiling point:
495.6±45.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml; Ethanol: 5 mg/ml
form 
A crystalline solid
pka
11.15±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10004177
Product name
CAY10443
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
10004177
Product name
CAY10443
Packaging
10mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
10004177
Product name
CAY10443
Packaging
25mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
10004177
Product name
CAY10443
Packaging
50mg
Price
$385
Updated
2024/03/01
AK Scientific
Product number
1066AH
Product name
(1S)-2,3-Dihydro-1H-inden-1-ylester((3,4-dichlorophenyl)methyl)-carbamicacid
Packaging
25mg
Price
$337
Updated
2021/12/16
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(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Chemical Properties,Usage,Production

Uses

Apoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].

Definition

ChEBI: Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1s)-2,3-dihydro-1h-inden-1-yl ester is a member of indanes.

References

[1] Nguyen JT, et al. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8. DOI:10.1073/pnas.1031631100

(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Suppliers

BOC Sciences
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1-631-485-4226; 16314854226
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BOC Sciences
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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774
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sales@glpbio.cn
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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TargetMol Chemicals Inc.
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Shanghai Yiyan Biotechnology Co. , Ltd.
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Shanghai Yifei Biotechnology Co. , Ltd.
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Cayman Chemical Company
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Shanghai Hongyu Biotechnology Co., Ltd.
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582314-48-5, (1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACIDRelated Search:


  • CAY10443
  • (1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
  • (S)-INDAN-1-YL 3,4-DICHLOROBENZYLCARBAMATE
  • CKERQCMQSBFFKX-INIZCTEOSA-N
  • Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1S)-2,3-dihydro-1H-inden-1-yl ester (9CI)
  • 582314-48-5