(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
- Product Name
- (1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
- CAS No.
- 582314-48-5
- Chemical Name
- (1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID
- Synonyms
- CAY10443;CKERQCMQSBFFKX-INIZCTEOSA-N;(S)-INDAN-1-YL 3,4-DICHLOROBENZYLCARBAMATE;(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID;Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1S)-2,3-dihydro-1H-inden-1-yl ester (9CI)
- CBNumber
- CB7308552
- Molecular Formula
- C17H15Cl2NO2
- Formula Weight
- 336.21
- MOL File
- Mol file
(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Property
- Boiling point:
- 495.6±45.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml; Ethanol: 5 mg/ml
- form
- A crystalline solid
- pka
- 11.15±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 10004177
- Product name
- CAY10443
- Packaging
- 5mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 10004177
- Product name
- CAY10443
- Packaging
- 10mg
- Price
- $92
- Updated
- 2024/03/01
- Product number
- 10004177
- Product name
- CAY10443
- Packaging
- 25mg
- Price
- $216
- Updated
- 2024/03/01
- Product number
- 10004177
- Product name
- CAY10443
- Packaging
- 50mg
- Price
- $385
- Updated
- 2024/03/01
- Product number
- 1066AH
- Product name
- (1S)-2,3-Dihydro-1H-inden-1-ylester((3,4-dichlorophenyl)methyl)-carbamicacid
- Packaging
- 25mg
- Price
- $337
- Updated
- 2021/12/16
(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Chemical Properties,Usage,Production
Uses
Apoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].
Definition
ChEBI: Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1s)-2,3-dihydro-1h-inden-1-yl ester is a member of indanes.
References
[1] Nguyen JT, et al. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8. DOI:10.1073/pnas.1031631100
(1S)-2,3-DIHYDRO-1H-INDEN-1-YL ESTER [(3,4-DICHLOROPHENYL)METHYL]-CARBAMIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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