ChemicalBook > CAS DataBase List > RX-518

RX-518

Product Name: RX-518
CAS No.: 1660963-42-7
Chemical Name: RX-518
Synonyms: CK101;CK-101;CK 101;RX-518;CS-2481;EGFR-IN-3;Olafertinib;RX518(CK-101);EGFR inhibitor 3;Olafertinib (RX-518)
CBNumber: CB73119786
Molecular Formula: C29H28F2N6O2
Formula Weight: 530.57
MOL File: 1660963-42-7.mol

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RX-518 Property

Density: 1.350±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (235.60 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 13.28±0.70(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0016788
Product name: Olafertinib
Purity: 99.94%
Packaging: 5mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0016788
Product name: Olafertinib
Purity: 99.94%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0016788
Product name: Olafertinib
Purity: 99.94%
Packaging: 25mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0016788
Product name: Olafertinib
Purity: 99.94%
Packaging: 50mg
Price: $900
Updated: 2021/12/16

ChemScene

Product number: CS-0016788
Product name: Olafertinib
Purity: 99.94%
Packaging: 100mg
Price: $1400
Updated: 2021/12/16

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RX-518 Chemical Properties,Usage,Production

Uses

Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research[1].

References

[1] Misako Nagasaka, et al. Beyond osimertinib: The development of 3 rd-generation EGFR Tyrosine Kinase Inhibitors. J Thorac Oncol. 2020 Dec 15;S1556-0864(20)31105-9. DOI:10.1016/j.jtho.2020.11.028

RX-518 Preparation Products And Raw materials

Raw materials

Preparation Products

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RX-518 Suppliers

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View Lastest Price from RX-518 manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: RX-518 1660963-42-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Career Henan Chemical Co

Product: EGFR-IN-3 1660963-42-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-01

1660963-42-7, RX-518Related Search:

N-[3-[2-[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]quinazolin-8-yl]phenyl]prop-2-enamide

EGFR-IN-3

RX-518

N-(3-(2-((2,3-Difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide

RX518(CK-101)

CK 101

CK101

CK-101

CK101;CK-101;CK 101;RX518;RX-518;RX 518

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EGFR inhibitor 3

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2-Propenamide, N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)-1-piperazinyl]phenyl]amino]-8-quinazolinyl]phenyl]-

Inhibitor,ErbB-1,Olafertinib,Epidermal growth factor receptor,NSCLC,HER1,EGFR,inhibit

RX518(CK-101:EGFR-IN-3)

Olafertinib (RX-518)

CK-101|||EGFR-IN-3|||RX-518

Olafertinib, 10 mM in DMSO

1660963-42-7

C29H28F2N6O2