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LB-100

Product Name
LB-100
CAS No.
1632032-53-1
Chemical Name
LB-100
Synonyms
LB-100（b）;LB-100 (1R,4S);LB-100 (LB100);LB-100;LB 100;LB100;endothall 4-methylpiperazine monoamide;(1r,4s)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid;rel-(1R,4S)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid;7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(4-methyl-1-piperazinyl)carbonyl]-, (1R,4S)-rel-
CBNumber
CB73121112
Molecular Formula
C13H20N2O4
Formula Weight
268.31
MOL File
1632032-53-1.mol
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LB-100 Property

Boiling point:
486.9±45.0 °C(Predicted)
Density 
1.312±0.06 g/cm3(Predicted)
storage temp. 
Store at -20 °C
solubility 
DMSO:54.0(Max Conc. mg/mL);201.26(Max Conc. mM)
form 
A crystalline solid
pka
4.03±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29105
Product name
LB-100
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
29105
Product name
LB-100
Packaging
50mg
Price
$841
Updated
2024/03/01
Cayman Chemical
Product number
29105
Product name
LB-100
Packaging
10mg
Price
$218
Updated
2024/03/01
Cayman Chemical
Product number
29105
Product name
LB-100
Packaging
25mg
Price
$481
Updated
2024/03/01
TRC
Product number
L009025
Product name
LB-100
Packaging
5mg
Price
$200
Updated
2021/12/16
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LB-100 Chemical Properties,Usage,Production

Uses

LB-100 is a small molecule inhibitor of protein phosphatase 2A with potent chemo- and radio-sensitizing potential in variety of cancer types including pancreatic cancer and colorectal cancer of human and animal model.

in vivo

LB-100 (2 mg/kg, i.p.) decreases in a time-dependent manner the activity of PP2A in xenografts and livers in nude mice. LB-100 does not alter the expression of the three PP2A subunits (PP2A_A, PP2A_B, and PP2A_C) in cell lines, xenografts, or livers, as confirmed by immunoblotting. The combination of doxorubicin (1.5 kg/mL, every other day) and LB-100 (2 mg/kg, every other day) significantly slows the growth of tumors with reduction of tumor volume in two animals with no effects on tumor growth in animals treated with single agents[2].

LB-100 Preparation Products And Raw materials

Raw materials

Preparation Products

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LB-100 Suppliers

China 38 United States 7 Global 45
Ningbo Chaoming Biotechnology Co., Ltd
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13301662590
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mandy@atkchemical.com
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China
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AdooQ Bioscience CHINA
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025-58849295 18951903616;
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025-68650336
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info@adooq.cn
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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klq@cw-bio.com
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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UHN Shanghai Research & Development Co., Ltd.
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021-58958002 18930822973
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021-58958618
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sales@uhnshanghai.com
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China
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Chengdu Saint - Kay Biotechnology Co., Ltd.
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028-85157043 15882256948
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676046971@qq.com
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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86-571-88216897,88216896 13588875226
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86-571-88216895
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sales@hzclap.com
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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Jingmo (Xiamen) Biotechnology Co., Ltd
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13621943973; 13621943973
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Shanghai Luofa Biochemical Technology Co., Ltd.
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
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021-51816796-820 13611835272
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Jinan Jiuli Biotechnology Co. , Ltd.
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Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd.
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159-00573766 18018507602
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Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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InvivoChem
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sales@invivochem.cn
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TargetMol Chemicals Inc.
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marketing@tsbiochem.com
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Shanghai Maclean Biochemical Technology Co., LTD
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021-021-50706066 15221275939
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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PharmaBlock Sciences (Nanjing), Inc.
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Nanjing Shizhou Biology Technology Co.,Ltd
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RD International Technology Co., Limited
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Cayman Chemical Company
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800-364-9897
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Biosynth Biological Technology (Suzhou) Co Ltd
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Adooq Bioscience LLC
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400-025-6535
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Selleck Chemicals
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Santa Cruz Biotechnology Inc
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ATK CHEMICAL COMPANY LIMITED
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HANGZHOU LEAP CHEM CO., LTD.
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ShenZhen Trendseen Biological Technology Co.,Ltd.
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Absin Bioscience Inc.
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1632032-53-1, LB-100Related Search:


  • endothall 4-methylpiperazine monoamide
  • LB-100;LB 100;LB100
  • LB-100 (LB100)
  • 7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(4-methyl-1-piperazinyl)carbonyl]-, (1R,4S)-rel-
  • LB-100 (1R,4S)
  • rel-(1R,4S)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid
  • LB-100（b）
  • (1r,4s)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid
  • 1632032-53-1