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PI3Kα inhibitor 1

Product Name
PI3Kα inhibitor 1
CAS No.
1235449-52-1
Chemical Name
PI3Kα inhibitor 1
Synonyms
MDK9521;CUDC-908;BEBT-908;PI3Kα-IN-243;PI3Kα inhibitor;PI3Kα inhibitor 1;BEBT-908(CUDC-908);PI3K-alpha inhibitor 1;BEBT-908, 10 mM in DMSO;BEBT-908 / PI3Kα inhibitor 1
CBNumber
CB73121127
Molecular Formula
C23H25N9O3S
Formula Weight
507.57
MOL File
1235449-52-1.mol
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PI3Kα inhibitor 1 Property

Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 37 mg/mL (72.90 mM)
pka
7.77±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5445
Product name
BEBT-908
Purity
>98.0%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-5445
Product name
BEBT-908
Purity
>98.0%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-5445
Product name
BEBT-908
Purity
>98.0%
Packaging
50mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-5445
Product name
BEBT-908
Purity
>98.0%
Packaging
100mg
Price
$2520
Updated
2021/12/16
Crysdot
Product number
CD31004144
Product name
PI3Kαinhibitor1
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
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PI3Kα inhibitor 1 Chemical Properties,Usage,Production

Uses

Ifupinostat is a selective PI3Kα inhibitor extracted from patent US/20120088764A1, Compound 243, has an IC50<0.1 μM, PI3Kα inhibitor 1 also inhibits HDAC (0.1 μM≤IC50≤1 μM) .

IC 50

PI3Kα: 0.1 μM (IC50); HDAC: 0.1 μM (IC50)

References

[1] Cai Xiong, et al. Deazapurines, thienopyrimidines and furopyrimidines as phosphoinositide 3-kinase inhibitors with a zinc binding moiety and their preparation and use in the treatment of diseases. From U.S. Pat. Appl. Publ. (2012), US 20120088764 A1 20120412.

PI3Kα inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PI3Kα inhibitor 1 Suppliers

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View Lastest Price from PI3Kα inhibitor 1 manufacturers

Career Henan Chemical Co
Product
PI3Kα inhibitor 1 1235449-52-1
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

1235449-52-1, PI3Kα inhibitor 1Related Search:


  • CUDC-908
  • BEBT-908(CUDC-908)
  • N-Hydroxy-2-[[[2-[6-(methylamino)pyridin-3-yl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl][methyl]amino]pyrimidine-5-carboxamide
  • N-hydroxy-2-[methyl({2-[6-(methylamino)pyridin-3-yl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl}methyl)amino]pyrimidine-5-carboxamide
  • BEBT908;CUDC908;BEBT 908;CUDC 908
  • PI3Kα-IN-243
  • BEBT-908
  • N-Hydroxy-2-[methyl[[2-[6-(methylamino)-3-pyridinyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]amino]-5-pyrimidinecarboxamide
  • BEBT-908 / PI3Kα inhibitor 1
  • PI3Kα inhibitor 1
  • MDK9521
  • Inhibitor,BEBT 908,BEBT908,BEBT-908,PI3K,inhibit,Phosphoinositide 3-kinase
  • 5-Pyrimidinecarboxamide, N-hydroxy-2-[methyl[[2-[6-(methylamino)-3-pyridinyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]amino]-
  • PI3Kα inhibitor
  • BEBT-908, 10 mM in DMSO
  • PI3K-alpha inhibitor 1
  • 1235449-52-1
  • C23H25N9O3S