ChemicalBook > CAS DataBase List > AlPhos
AlPhos
Reaction- Product Name
- AlPhos
- CAS No.
- 1805783-60-1
- Chemical Name
- AlPhos
- Synonyms
- 6-Methoxy-2-{2,4,6-tri-i-propyl-3-[(2,3,5,6-tetrafluoro-4-butyl;3',1''-terphenyl]-2-yl]bis(tricyclo[3.3.1.1(3,7)]dec-1-yl)phosphine;6-Methoxy-2-{2,4,6-tri-i-propyl-3-[(2,3,5,6-tetrafluoro-4-butyl,AlPhos;[4''-Butyl-2'',3'',5'',6''-tetrafluoro-3-methoxy-2',4',6'-tris(1-methylethyl)[1,1';6-Methoxy-2-{2,4,6-tripropyl-3-[(2,3,5,6-tetrafluorocyclopentyl)phenyl]phenyl}diphenylphosphine;6-methoxy-2-{2,4,6-triisopropyl-3-[(2,3,5,6-tetrafluoro-4-butyl)phenyl]phenyl}dicyclohexylphosphine;2-(Diadamantylphosphino)-3-methoxy-2,4,6-tri-i-propyl-3-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1-biph;6-Methoxy-2-{2,4,6-tri-i-propyl-3-[(2,3,5,6-tetrafluoro-4-butyl )phenyl]phenyl}diadamantyl phosphine;6-Methoxy-2-{2,4,6-tri-i-propyl-3-[(2,3,5,6-tetrafluoro-4-butyl)phenyl]phenyl}diadamantylphosphine,98%;6-Methoxy-2-{2,4,6-tri-i-propyl-3-[(2,3,5,6-tetrafluoro-4-butyl )phenyl]phenyl}diadamantyl phosphine, 98%
- CBNumber
- CB73139858
- Molecular Formula
- C52H67F4OP
- Formula Weight
- 815.06
- MOL File
- 1805783-60-1.mol
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AlPhos Property
- Melting point:
- 218-223 °C
- storage temp.
- -20°C
- form
- Powder
- color
- white to yellow
- Sensitive
- air sensitive
- InChIKey
- ALWIRDZSIXWCBO-UHFFFAOYSA-N
- SMILES
- P(C1=C(OC)C=CC=C1C1=C(C(C)C)C=C(C(C)C)C(C2=C(F)C(F)=C(CCCC)C(F)=C2F)=C1C(C)C)(C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2
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Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 799718
- Product name
- AlPhos
- Packaging
- 100MG
- Price
- $191
- Updated
- 2026/04/30
Strem Chemicals
- Product number
- 15-2065
- Product name
- 2-(Diadamantylphosphino)-3-methoxy-2’,4’,6’-tri-i-propyl-3’-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1’-biphenyl, AlPhos
- Packaging
- 100mg
- Price
- $116
- Updated
- 2026/04/30
Strem Chemicals
- Product number
- 15-2065
- Product name
- 2-(Diadamantylphosphino)-3-methoxy-2’,4’,6’-tri-i-propyl-3’-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1’-biphenyl, AlPhos
- Packaging
- 500mg
- Price
- $455
- Updated
- 2026/04/30
Strem Chemicals
- Product number
- 15-2065
- Product name
- 2-(Diadamantylphosphino)-3-methoxy-2’,4’,6’-tri-i-propyl-3’-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1’-biphenyl, AlPhos
- Packaging
- 2g
- Price
- $1360
- Updated
- 2026/04/30
Strem Chemicals
- Product number
- 15-2065
- Product name
- 2-(Diadamantylphosphino)-3-methoxy-2,4,6-tri-i-propyl-3-(2,3,5,6-tetrafluoro-4-butylphenyl)-1,1-biphenyl AlPhos
- Packaging
- 100mg
- Price
- $114
- Updated
- 2024/03/01
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AlPhos Chemical Properties,Usage,Production
Reaction
- Ligand for the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides
- Ligand for the Palladium-Catalyzed Fluorination of Aryl Triflates and Bromides
Uses
AlPhos is used in the selective arylation of aminophenylalanine in unprotected peptides with organometallic palladium reagents.
General Description
AlPhos is a versatile, highly efficient ligand used extensively in various important organic transformations. Recognized for its unique structure and attributes, AlPhos serves as an impressive catalyst that enables several key synthetic processes. It is primarily used in the following coupling reactions: Buchwald-Hartwig cross coupling, Suzuki-Miyaura coupling, Stille coupling, Sonogashira coupling, Negishi coupling, Heck coupling, Hiyama coupling reaction. With its remarkable performance across these reactions, AlPhos represents an invaluable tool in preparing and producing pharmaceuticals, agrochemicals, and polymers.
reaction suitability
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings
AlPhos Preparation Products And Raw materials
Raw materials
Preparation Products
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AlPhos Suppliers
- Tel
- 0512-67216630 67216634
- Fax
- 0512-56316689
- sales@sinocompound.com
- Country
- China
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- 258
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- 025-66028182 17714375163
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- China
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- 021-61415566 800-8193336
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- China
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- 51395
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- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
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- China
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- 0371-65511006 18737115891;18625597674
- info@kingorgchem.com;sales@kingorgchem.com
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- China
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- 010-60605840 18892239720
- Fax
- 010-60605840
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- China
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- 021-60702684 18516024827
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- China
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- QQ 2816925681
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- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
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- Tel
- 18017061086
- oled@richest-group.com
- Country
- CHINA
- ProdList
- 5600
- Advantage
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View Lastest Price from AlPhos manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- [4''-Butyl-2'',3'',5'',6''-tetrafluoro-3-methoxy-2',4',6'-tris(1-methylethyl)[1,1':3',1''-terphenyl]-2-yl]bis(tricyclo[3.3.1.1(3,7)]dec-1-yl)phosphine 1805783-60-1
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-20