ChemicalBook > CAS DataBase List > 1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

Product Name: 1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester
CAS No.: 132819-92-2
Chemical Name: 1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester
Synonyms: NOD-IN-1;MDK19922;NOD inhibitor 1;NOD-IN-1, 10 mM in DMSO;Ethyl 1-tosyl-1H-indole-2-carboxylate;ethyl 1-(4-methylphenyl)sulfonylindole-2-carboxylate;NOD-IN-1; COMPOUND 4; MDK19922; MDK 19922; MDK-19922.;NODIN1,inhibit,NOD IN 1,Inhibitor,NOD-like Receptor (NLR);1-(toluene-4-sulfonyl)-1H-indole-2-carboxylic acid ethyl ester;1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester
CBNumber: CB73145909
Molecular Formula: C18H17NO4S
Formula Weight: 343.4
MOL File: 132819-92-2.mol

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1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester Property

Melting point:: 98-99 °C
Boiling point:: 523.3±52.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28370
Product name: NOD-IN-1
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 28370
Product name: NOD-IN-1
Packaging: 25mg
Price: $638
Updated: 2024/03/01

Cayman Chemical

Product number: 28370
Product name: NOD-IN-1
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 28370
Product name: NOD-IN-1
Packaging: 10mg
Price: $292
Updated: 2024/03/01

AK Scientific

Product number: 5220CV
Product name: Nod-IN-1
Packaging: 250mg
Price: $297
Updated: 2021/12/16

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1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester Chemical Properties,Usage,Production

Uses

NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.

IC 50

NOD1; NOD2

References

[1] Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234. DOI:10.1016/j.bmc.2016.08.044

1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester Suppliers

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132819-92-2, 1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl esterRelated Search:

1-(toluene-4-sulfonyl)-1H-indole-2-carboxylic acid ethyl ester

MDK19922

NOD-IN-1; COMPOUND 4; MDK19922; MDK 19922; MDK-19922.

NOD inhibitor 1

1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

NOD-IN-1

NODIN1,inhibit,NOD IN 1,Inhibitor,NOD-like Receptor (NLR)

ethyl 1-(4-methylphenyl)sulfonylindole-2-carboxylate

Ethyl 1-tosyl-1H-indole-2-carboxylate

NOD-IN-1, 10 mM in DMSO

NOD-IN-1 (1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester)

132819-92-2