ChemicalBook > CAS DataBase List > Vadadustat

Vadadustat

Product Name
Vadadustat
CAS No.
1000025-07-9
Chemical Name
Vadadustat
Synonyms
CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;PG 1016548;Vadadustat;Vardorestat;Vadadustat 13C6;PG-1016548;AKB-6548
CBNumber
CB73147387
Molecular Formula
C14H11ClN2O4
Formula Weight
306.7
MOL File
1000025-07-9.mol
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Vadadustat Property

Melting point:
172-174°C
Boiling point:
674.6±55.0 °C(Predicted)
Density 
1.461±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.09±0.40(Predicted)
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
25mg
Price
$239
Updated
2024/03/01
Cayman Chemical
Product number
15295
Product name
Vadadustat
Packaging
50mg
Price
$357
Updated
2024/03/01
TRC
Product number
V849530
Product name
Vadadustat
Packaging
5mg
Price
$195
Updated
2021/12/16
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Vadadustat Chemical Properties,Usage,Production

Description

Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.

Uses

Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.

Vadadustat Preparation Products And Raw materials

Raw materials

Preparation Products

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Vadadustat Suppliers

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View Lastest Price from Vadadustat manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
Product
Vadadustat 1000025-07-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000kgs
Release date
2021-05-24
Career Henan Chemical Co
Product
Vadadustat 1000025-07-9
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

1000025-07-9, VadadustatRelated Search:


  • AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; VADADUSTAT
  • PG-1016548;AKB-6548
  • Vadadustat
  • Vadadustat(AKB-6548/PG-1016548)
  • Vadadustat (AKB-6548)
  • AKB-6548
  • PG 1016548
  • PG1016548
  • PG-1016548
  • PG-1016548; PG1016548; PG 1016548; AKB-6548
  • CS-2486
  • Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-
  • Vadadustat USP/EP/BP
  • Vadadustat (PG-1016548
  • Vadadustat 13C6
  • Valdesta
  • disease,HIFs,AKB 6548,Erythropoiesis-stimulating,kidney,Inhibitor,AKB6548,inhibit,Vadadustat,HIF-PH,PG 1016548,anemia,Hypoxia-inducible factors,PG1016548,nondialysis-dependent,HIF/HIF Prolyl-Hydroxylase,chronic
  • Vardorestat
  • 2-(5-(3-chlorophenyl)-3-hydroxypicolinamido)acetic acid
  • 1000025-07-9
  • API