ChemicalBook > CAS DataBase List > Vadadustat
Vadadustat
- Product Name
- Vadadustat
- CAS No.
- 1000025-07-9
- Chemical Name
- Vadadustat
- Synonyms
- CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;PG 1016548;Vadadustat;Vardorestat;Vadadustat 13C6;PG-1016548;AKB-6548
- CBNumber
- CB73147387
- Molecular Formula
- C14H11ClN2O4
- Formula Weight
- 306.7
- MOL File
- 1000025-07-9.mol
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Vadadustat Property
- Melting point:
- 172-174°C
- Boiling point:
- 674.6±55.0 °C(Predicted)
- Density
- 1.461±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.09±0.40(Predicted)
- color
- Pale Beige to Light Beige
- Stability:
- Hygroscopic
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314Get medical advice/attention if you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 15295
- Product name
- Vadadustat
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15295
- Product name
- Vadadustat
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15295
- Product name
- Vadadustat
- Packaging
- 25mg
- Price
- $239
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15295
- Product name
- Vadadustat
- Packaging
- 50mg
- Price
- $357
- Updated
- 2024/03/01
TRC
- Product number
- V849530
- Product name
- Vadadustat
- Packaging
- 5mg
- Price
- $195
- Updated
- 2021/12/16
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Vadadustat Chemical Properties,Usage,Production
Description
Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.
Uses
Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.
Vadadustat Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Vadadustat manufacturers
Wuhan Nutra Biotechnology Co.,Ltd
- Product
- Vadadustat 1000025-07-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1000kgs
- Release date
- 2021-05-24
Career Henan Chemical Co
- Product
- Vadadustat 1000025-07-9
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08