R-Acalabrutinib

Product Name: R-Acalabrutinib
CAS No.: 1952316-43-6
Chemical Name: R-Acalabrutinib
Synonyms: R-Acalabrutinib;Acalabrutinib R-Isomer;Acalabrutinib enantiomer;Acalabrutinib Impurity N1;Acalabrutinib enantiomer, 10 mM in DMSO;(R)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide;Benzamide, 4-[8-amino-3-[(2R)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-
CBNumber: CB73147473
Molecular Formula: C26H23N7O2
Formula Weight: 465.51
MOL File: 1952316-43-6.mol

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R-Acalabrutinib Property

Density: 1.37±0.1 g/cm3(Predicted)
pka: 11.47±0.70(Predicted)
InChIKey: WDENQIQQYWYTPO-LJQANCHMSA-N
SMILES: C(NC1=NC=CC=C1)(=O)C1=CC=C(C2=C3N(C([C@H]4CCCN4C(=O)C#CC)=N2)C=CN=C3N)C=C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS59511
Product name: Acalabrutinib enantiomer
Purity: 95+%
Packaging: 25mg
Price: $403
Updated: 2021/12/16

Activate Scientific

Product number: AS59511
Product name: Acalabrutinib enantiomer
Purity: 95+%
Packaging: 100mg
Price: $891
Updated: 2021/12/16

Chemenu

Product number: CM330069
Product name: 4-[8-amino-3-[(2R)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
Purity: 95%+
Packaging: 100mg
Price: $1463
Updated: 2021/12/16

Chemenu

Product number: CM330069
Product name: 4-[8-amino-3-[(2R)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
Purity: 95%+
Packaging: 250mg
Price: $2535
Updated: 2021/12/16

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R-Acalabrutinib Chemical Properties,Usage,Production

Uses

(R)-Acalabrutinib ((R)-ACP-196) is the enantiomer of Acalabrutinib (HY-17600). (R)-Acalabrutinib is an inhibitor for Bruton’s tyrosine kinase (BTK)[1].

References

[1] Rayala VVSPK, et al., A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib. Chirality. 2022 Sep;34(9):1247-1256. DOI:10.1002/chir.23485

R-Acalabrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

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R-Acalabrutinib Suppliers

China 32 India 1 United States 2 Global 35

Aurisco Pharmaceutical (Tianjin) Inc.

Tel: 022-59885855
Country: China
ProdList: 96
Advantage: 58

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
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Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-86818997 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2989
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 1788
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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
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Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15727060112
Email: yutianchun2007@126.com
Country: China
ProdList: 9815
Advantage: 58

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View Lastest Price from R-Acalabrutinib manufacturers

Moxin Chemicals

Product: (R)-Acalabrutinib 1952316-43-6
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 10000
Release date: 2025-03-06

1952316-43-6, R-AcalabrutinibRelated Search:

R-Acalabrutinib

Acalabrutinib enantiomer

(R)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

Benzamide, 4-[8-amino-3-[(2R)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-

Acalabrutinib Impurity N1

Acalabrutinib enantiomer, 10 mM in DMSO

Acalabrutinib R-Isomer

1952316-43-6