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MIN-101

Product Name
MIN-101
CAS No.
359625-79-9
Chemical Name
MIN-101
Synonyms
MT210;MT-210;MT 210;CYR-101;MIN-101;Roluperidone;CYR-101(Roluperidone);Roluperidone (MIN101);Roluperidone (CYR-101);Roluperidone, 10 mM in DMSO
CBNumber
CB73147776
Molecular Formula
C22H23FN2O2
Formula Weight
366.43
MOL File
359625-79-9.mol
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MIN-101 Property

storage temp. 
Store at -20°C
solubility 
DMSO:33.33(Max Conc. mg/mL);90.96(Max Conc. mM)
form 
A solid
color 
White to yellow
InChI
InChI=1S/C22H23FN2O2/c23-19-7-5-17(6-8-19)21(26)15-24-11-9-16(10-12-24)13-25-14-18-3-1-2-4-20(18)22(25)27/h1-8,16H,9-15H2
InChIKey
RNRYULFRLCBRQS-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)CN1CC1CCN(CC(C2=CC=C(F)C=C2)=O)CC1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29773
Product name
CYR-101
Packaging
10mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
29773
Product name
CYR-101
Packaging
100mg
Price
$621
Updated
2024/03/01
Cayman Chemical
Product number
29773
Product name
CYR-101
Packaging
25mg
Price
$209
Updated
2024/03/01
Cayman Chemical
Product number
29773
Product name
CYR-101
Packaging
50mg
Price
$363
Updated
2024/03/01
ChemScene
Product number
CS-6971
Product name
Roluperidone
Purity
98.08%
Packaging
50mg
Price
$900
Updated
2021/12/16
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MIN-101 Chemical Properties,Usage,Production

Uses

Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively).

IC 50

5-HT2A Receptor: 7.53 nM (Ki); Sigma-2 Receptor: 8.19 nM (Ki)

References

[1] Davidson M, et al. Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia. Am J Psychiatry. 2017 Jul 28:appiajp201717010122. DOI:10.1176/appi.ajp.2017.17010122

MIN-101 Preparation Products And Raw materials

Raw materials

Preparation Products

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MIN-101 Suppliers

Taizhou Nanfeng Pharmaceutical Research Institute
Tel
nanfengdrug@163.com; 18616377689
Email
nanfengdrug@163.com
Country
China
ProdList
20009
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Bayee Biotech (Anqing) Co., Ltd.
Tel
0556-5032306 18917961636
Email
wtx@bayeebio.com
Country
China
ProdList
239
Advantage
61
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1077
Advantage
64
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai Biolang biotechnology Co.,Ltd
Tel
17764003753
Fax
13669031409
Email
2326587775@qq.com
Country
China
ProdList
188
Advantage
55
Shanghai Biolang biotechnology Co.,Ltd
Tel
17764003753
Fax
13669031409
Email
2326587775@qq.com
Country
China
ProdList
188
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58

359625-79-9, MIN-101Related Search:


  • MIN-101
  • CYR-101
  • Roluperidone (CYR-101)
  • MIN-101; MIN 101; MIN101; CYR-101; CYR 101; CYR101; MT-210; MT 210; MT210;
  • MT 210
  • MT210
  • MT-210
  • Roluperidone
  • 1H-Isoindol-1-one, 2-[[1-[2-(4-fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-
  • CYR-101(Roluperidone)
  • MT210,MIN 101,5-hydroxytryptamine Receptor,CYR 101,MT 210,CYR101,Inhibitor,MIN101,inhibit,5-HT Receptor,Sigma Receptor,Roluperidone,Serotonin Receptor
  • Roluperidone (MIN101)
  • 2-((1-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one
  • Roluperidone, 10 mM in DMSO
  • 359625-79-9
  • APIS