MIN-101
- Product Name
- MIN-101
- CAS No.
- 359625-79-9
- Chemical Name
- MIN-101
- Synonyms
- MT210;MT-210;MT 210;CYR-101;MIN-101;Roluperidone;CYR-101(Roluperidone);Roluperidone (MIN101);Roluperidone (CYR-101);Roluperidone, 10 mM in DMSO
- CBNumber
- CB73147776
- Molecular Formula
- C22H23FN2O2
- Formula Weight
- 366.43
- MOL File
- 359625-79-9.mol
MIN-101 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:33.33(Max Conc. mg/mL);90.96(Max Conc. mM)
- form
- A solid
- color
- White to yellow
- InChI
- InChI=1S/C22H23FN2O2/c23-19-7-5-17(6-8-19)21(26)15-24-11-9-16(10-12-24)13-25-14-18-3-1-2-4-20(18)22(25)27/h1-8,16H,9-15H2
- InChIKey
- RNRYULFRLCBRQS-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=CC=C2)CN1CC1CCN(CC(C2=CC=C(F)C=C2)=O)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H320Causes eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 29773
- Product name
- CYR-101
- Packaging
- 10mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 29773
- Product name
- CYR-101
- Packaging
- 100mg
- Price
- $621
- Updated
- 2024/03/01
- Product number
- 29773
- Product name
- CYR-101
- Packaging
- 25mg
- Price
- $209
- Updated
- 2024/03/01
- Product number
- 29773
- Product name
- CYR-101
- Packaging
- 50mg
- Price
- $363
- Updated
- 2024/03/01
- Product number
- CS-6971
- Product name
- Roluperidone
- Purity
- 98.08%
- Packaging
- 50mg
- Price
- $900
- Updated
- 2021/12/16
MIN-101 Chemical Properties,Usage,Production
Uses
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively).
IC 50
5-HT2A Receptor: 7.53 nM (Ki); Sigma-2 Receptor: 8.19 nM (Ki)
References
[1] Davidson M, et al. Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia. Am J Psychiatry. 2017 Jul 28:appiajp201717010122. DOI:10.1176/appi.ajp.2017.17010122
MIN-101 Preparation Products And Raw materials
Raw materials
Preparation Products
MIN-101 Suppliers
- Tel
- nanfengdrug@163.com; 18616377689
- nanfengdrug@163.com
- Country
- China
- ProdList
- 20009
- Advantage
- 58
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2922
- Advantage
- 55
- Tel
- 0556-5032306 18917961636
- wtx@bayeebio.com
- Country
- China
- ProdList
- 239
- Advantage
- 61
- Tel
- 17702719238 18971495150;
- sales@sun-shinechem.com
- Country
- China
- ProdList
- 1077
- Advantage
- 64
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4861
- Advantage
- 58
- Tel
- 17764003753
- Fax
- 13669031409
- 2326587775@qq.com
- Country
- China
- ProdList
- 188
- Advantage
- 55
- Tel
- 17764003753
- Fax
- 13669031409
- 2326587775@qq.com
- Country
- China
- ProdList
- 188
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58