UNC-2371A

ChemicalBook > CAS DataBase List > UNC-2371A

Product Name: UNC-2371A
CAS No.: 1429882-07-4
Chemical Name: UNC-2371A
Synonyms: UNC2371;MRX-2843;UNC-2371A;UNC2371;MRX-2843;MRX-2843 (UNC2371);MRX-2843?(Synonyms: UNC2371;(1r,4r)-4-(2-(2-cyclopropylethylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol;Cyclohexanol, 4-[2-[(2-cyclopropylethyl)amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-;UNC 2371,FLT3,Fms like tyrosine kinase 3,CD135,inhibit,MRX2843,Cluster of differentiation antigen 135,UNC-2371,Inhibitor,MRX-2843,MRX 2843
CBNumber: CB73168663
Molecular Formula: C29H40N6O
Formula Weight: 488.67
MOL File: 1429882-07-4.mol

Less

UNC-2371A Property

Melting point:: >137°C (dec.)
Boiling point:: 697.3±65.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka: 14.63±0.40(Predicted)
form: Solid
color: White to Pale Beige

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 27923
Product name: MRX-2843
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 27923
Product name: MRX-2843
Packaging: 10mg
Price: $333
Updated: 2024/03/01

Cayman Chemical

Product number: 27923
Product name: MRX-2843
Packaging: 5mg
Price: $179
Updated: 2024/03/01

TRC

Product number: M750145
Product name: MRX-2843
Packaging: 25mg
Price: $545
Updated: 2021/12/16

ChemScene

Product number: CS-8117
Product name: MRX-2843
Purity: 99.70%
Packaging: 10mg
Price: $672
Updated: 2021/12/16

Less

UNC-2371A Chemical Properties,Usage,Production

Description

MRX-2843 is an inhibitor of Mer and FMS-like tyrosine kinase 3 (FLT3; IC₅₀s = 1.3 and 1 nM, respectively). It also inhibits Axl and Tyro3 (IC₅₀s = 15 and 17 nM, respectively). MRX-2843 (10-300 nM) inhibits Mer phosphorylation in MOLM-14 and MV4-11 acute myeloid leukemia (AML) cells and reduces clonal expansion of Kasumi-1 AML cells (IC₅₀ = 143.5 nM). In vivo, MRX-2843 increases survival in NOMO-1 and MOLM-14 AML mouse xenograft models when administered at doses of 65 and 50 mg/kg, respectively.

Uses

MRX-2843, is an orally available small-molecule inhibitor of both MERTK and FLT3.

UNC-2371A Preparation Products And Raw materials

Raw materials

Preparation Products

Less

UNC-2371A Suppliers

China 37 United States 4 Global 41

ChemCell Biomedicine Co.,Ltd.

Tel: 020-13556033878 2965585218 13556033878
Fax: 0086-0757-85406358
Email: chemcell@hotmail.com
Country: China
ProdList: 369
Advantage: 52

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9756
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1836
Advantage: 55

Dezhou LonWel Pharmaceutical Technology Co., Ltd.

Tel: 13761310616
Fax: QQ: 39324283
Email: 39324283@qq.com
Country: China
ProdList: 1953
Advantage: 58

Nanjing SynTitan Pharmaceutical Co., Ltd.

Tel: 25-57027686 17372956142
Fax: 025-57027686
Email: li_lan@syntitan.com
Country: China
ProdList: 7692
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 10067
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10523
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5182
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14253
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Shanghai Zeye Biotechnology Co., Ltd.

Tel: 021-61998551 13122364865
Email: sale1@shzysw.net
Country: China
ProdList: 9763
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 2414
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: chenjw@absin.cn
Country: China
ProdList: 24734
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Shanghai Luofa Biochemical Technology Co., Ltd.

Tel: 021-51111890 15317326293
Email: sales@molnova.com
Country: China
ProdList: 4196
Advantage: 58

Advanced chemblocks inc

Tel: 650-6922368
Email: sales@achemblock.com
Country: China
ProdList: 2992
Advantage: 58

Shanghai Dexuan Pharmaceutical Technology Co., Ltd

Tel: 1701086315
Fax: 1701086315@qq.com
Email: dexuanpharma@126.com
Country: China
ProdList: 9478
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44489
Advantage: 58

Nanjing houxiu Pharmaceutical Technology Co., Ltd

Tel: 15252458249
Email: 323325018@qq.com
Country: China
ProdList: 1168
Advantage: 58

Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd.

Tel: 025-025-58280381 15720605021
Fax: QQ：353175721
Email: zhang_lei@jsnchem.com
Country: China
ProdList: 1504
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6712
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9892
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24023
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 4164
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 8740
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: sun_dan@PharmaBlock.com
Country: China
ProdList: 7268
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 5019
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12007
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: 3674309880
Email: hanfangpharma@126.com
Country: China
ProdList: 30968
Advantage: 58

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9623
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32686
Advantage: 60

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43348
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

Wuxi Laifusi Biological Experimental Equipment Co., Ltd.

Tel: --
Fax: --
Email: marketing@lifesbiology.com
Country: CHINA
ProdList: 668
Advantage: 58

1429882-07-4, UNC-2371ARelated Search:

(1r,4r)-4-(2-(2-cyclopropylethylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol

UNC-2371A

MRX-2843 (UNC2371)

MRX-2843

UNC2371

UNC2371;MRX-2843

Cyclohexanol, 4-[2-[(2-cyclopropylethyl)amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-

MRX-2843?(Synonyms: UNC2371

UNC 2371,FLT3,Fms like tyrosine kinase 3,CD135,inhibit,MRX2843,Cluster of differentiation antigen 135,UNC-2371,Inhibitor,MRX-2843,MRX 2843

1429882-07-4

C29H40N6O