ChemicalBook > CAS DataBase List > AMG-009

AMG-009

Product Name
AMG-009
CAS No.
1027847-67-1
Chemical Name
AMG-009
Synonyms
AMG-009;AMG009,AMG 009;2-(4-(4-(Butylcarbamoyl)-2-((2,4-dichlorophenyl)sulfonamido)phenoxy)-3-methoxyphenyl)acetic acid;Benzeneacetic acid, 4-[4-[(butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-
CBNumber
CB73175524
Molecular Formula
C26H26Cl2N2O7S
Formula Weight
581.46
MOL File
1027847-67-1.mol
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AMG-009 Property

Melting point:
148.6 °C
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.20±0.10(Predicted)
form 
Solid
color 
Pale Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
42392
Product name
AMG 009
Purity
≥98%
Packaging
5mg
Price
$83
Updated
2026/04/30
Cayman Chemical
Product number
42392
Product name
AMG 009
Purity
≥98%
Packaging
10mg
Price
$158
Updated
2026/04/30
Cayman Chemical
Product number
42392
Product name
AMG 009
Purity
≥98%
Packaging
50mg
Price
$455
Updated
2026/04/30
Cayman Chemical
Product number
42392
Product name
AMG 009
Purity
≥98%
Packaging
100mg
Price
$743
Updated
2026/04/30
TRC
Product number
A576555
Product name
4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneaceticAcid
Packaging
100mg
Price
$1320
Updated
2021/12/16
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AMG-009 Chemical Properties,Usage,Production

Uses

4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneacetic Acid is a dualprostanoid D receptor(DP) andchemoattractant receptor-homologous molecule expressed on Th2 cells(CRTH2) antagonist. DP and CRTH2 are involved in mediating allergic reactions (asthma, allergic rhinitis, and atopic dermatitis). Compounds that inhibit these receptors may hold potential for treating allergic diseases.

in vivo

AMG 009 (3, 10 or 30 mg/kg, s.c.) results in a dose dependent decrease in airway resistance provoked by PGD2 aerosol in an acute guinea pig model[1]. In a guinea pig model of PGD2-induced airway constriction, AMG 009 significantly improves DP potency, with Kb of 82 nM[2].

IC 50

DP: 12 nM (IC50); CRTH2: 3 nM (IC50)

AMG-009 Preparation Products And Raw materials

Raw materials

Preparation Products

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AMG-009 Suppliers

Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13770331960
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16059
Advantage
64
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
1143
Advantage
58

1027847-67-1, AMG-009Related Search:


  • AMG-009
  • Benzeneacetic acid, 4-[4-[(butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-
  • AMG009,AMG 009
  • 2-(4-(4-(Butylcarbamoyl)-2-((2,4-dichlorophenyl)sulfonamido)phenoxy)-3-methoxyphenyl)acetic acid
  • 1027847-67-1
  • C26H26Cl2N2O7S