AMG-009
- Product Name
- AMG-009
- CAS No.
- 1027847-67-1
- Chemical Name
- AMG-009
- Synonyms
- AMG-009;AMG009,AMG 009;2-(4-(4-(Butylcarbamoyl)-2-((2,4-dichlorophenyl)sulfonamido)phenoxy)-3-methoxyphenyl)acetic acid;Benzeneacetic acid, 4-[4-[(butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-
- CBNumber
- CB73175524
- Molecular Formula
- C26H26Cl2N2O7S
- Formula Weight
- 581.46
- MOL File
- 1027847-67-1.mol
AMG-009 Property
- Melting point:
- 148.6 °C
- Density
- 1.403±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.20±0.10(Predicted)
- form
- Solid
- color
- Pale Brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 42392
- Product name
- AMG 009
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $83
- Updated
- 2026/04/30
- Product number
- 42392
- Product name
- AMG 009
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $158
- Updated
- 2026/04/30
- Product number
- 42392
- Product name
- AMG 009
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $455
- Updated
- 2026/04/30
- Product number
- 42392
- Product name
- AMG 009
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $743
- Updated
- 2026/04/30
- Product number
- A576555
- Product name
- 4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneaceticAcid
- Packaging
- 100mg
- Price
- $1320
- Updated
- 2021/12/16
AMG-009 Chemical Properties,Usage,Production
Uses
4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneacetic Acid is a dualprostanoid D receptor(DP) andchemoattractant receptor-homologous molecule expressed on Th2 cells(CRTH2) antagonist. DP and CRTH2 are involved in mediating allergic reactions (asthma, allergic rhinitis, and atopic dermatitis). Compounds that inhibit these receptors may hold potential for treating allergic diseases.
in vivo
AMG 009 (3, 10 or 30 mg/kg, s.c.) results in a dose dependent decrease in airway resistance provoked by PGD2 aerosol in an acute guinea pig model[1]. In a guinea pig model of PGD2-induced airway constriction, AMG 009 significantly improves DP potency, with Kb of 82 nM[2].
IC 50
DP: 12 nM (IC50); CRTH2: 3 nM (IC50)
AMG-009 Preparation Products And Raw materials
Raw materials
Preparation Products
AMG-009 Suppliers
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