Phenoxazine

General Description Properties Uses Preparation Hazards

Product Name: Phenoxazine
CAS No.: 135-67-1
Chemical Name: Phenoxazine
Synonyms: 10H-Phenoxazine;PHENAZOXINE;2,3,5,6-DIBENZO-1,4-OXAZINE;PHENOXAZINE;1H-Phenoxazine;Phenoxazine>Phenoxazine 97%;Phenoxazine,97%;RARECHEM FH 2C 0S92;Phenoxazine, 97% 5GR
CBNumber: CB7329656
Molecular Formula: C12H9NO
Formula Weight: 183.21
MOL File: 135-67-1.mol

More

Less

Phenoxazine Property

Melting point:: 156-159 °C (lit.)
Boiling point:: 316.88°C (rough estimate)
Density: 1.1261 (rough estimate)
refractive index: 1.5880 (estimate)
RTECS: SP7450000
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: benzene: freely soluble(lit.)
form: Fine Crystalline Powder
pka: 1.80±0.20(Predicted)
color: Gray to green-gray
Water Solubility: Soluble in methanol. Insoluble in water.
Merck: 14,7253
BRN: 143234
InChIKey: TZMSYXZUNZXBOL-UHFFFAOYSA-N
CAS DataBase Reference: 135-67-1(CAS DataBase Reference)
NIST Chemistry Reference: Phenoxazine(135-67-1)

More

Less

Safety

Safety Statements: 22-24/25-25-24
WGK Germany: 3
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P14858
Product name: Phenoxazine
Purity: 97%
Packaging: 1g
Price: $58.9
Updated: 2024/03/01

TCI Chemical

Product number: P0899
Product name: Phenoxazine
Purity: >98.0%(GC)
Packaging: 1g
Price: $44
Updated: 2024/03/01

TCI Chemical

Product number: P0899
Product name: Phenoxazine
Purity: >98.0%(GC)
Packaging: 5g
Price: $126
Updated: 2024/03/01

Alfa Aesar

Product number: L01969
Product name: Phenoxazine, 98%
Packaging: 1g
Price: $49.65
Updated: 2024/03/01

Alfa Aesar

Product number: L01969
Product name: Phenoxazine, 98%
Packaging: 5g
Price: $190
Updated: 2024/03/01

More

Less

Phenoxazine Chemical Properties,Usage,Production

General Description

Phenoxazine (C12H9NO) is a heterocyclic compound whose structure consists of an oxazine bonded to 2 benzene rings. It forms the nucleus of a wide variety of pharmaceutical molecules and dye-stuffs. It is a grey to off-white powder with a purity of 98% that acts as a transitional agent for 4,6-bis(diphenylphosphino)phenazine, and it can also be applied as a transitional agent for catalysts, pharmaceuticals, and oled.

Properties

Phenoxazine has a molecular weight of 183.21 g/mol and a monoisotopic mass of 183.068 g/mol, which is also its exact mass. The compound has a heavy atom count of 14 and a complexity of 187. Phenoxazine has a melting point of 1560 C and it dissolves in water at the rate of 2.130 mg/l at 250 C

Uses

Phenoxazine and its derivatives are not widely used hence the oxazine dyes are the only commercially viable derivatives. Certain oxazine dyes such as Nile blue dye is used in the preferential staining of brain cancer tissue since some of these dyes can inhibit the growth of these tumors. Various studies have explored the methods of preparation of boronic acids in a way that can result in a boron derivative of Phenoxazine (Nile blue dyes) which can be beneficial in cancer chemotherapy.

Preparation

The preparation of Phenoxazine and its by-products revolves around cyclization reactions. Each reaction is distinct from the other based on the starting materials and the conditions applied to the preparation process. Most cyclization reactions involved in the production of Phenoxazine and its by-products take place through one crucial step reactions as opposed to a series of steps where an aryl ether or an aryl amine would be obtained.

Hazards

The toxicological effects of Phenoxazine have not been investigated thoroughly but exposure to the compound may harm the eyes, skin, digestive tract and respiratory tract through irritation.

Chemical Properties

grey to green-grey fine crystalline powder

Uses

Phenoxazine is a tricyclic 2′deoxycytidine analog that has been used to improve stacking interactions between heterocycles of oligonucleotide/RNA hybrids and to enhance cellular uptake.

Definition

ChEBI: 10H-phenoxazine is a member of the class of phenoxazines that is morpholine which is ortho-fused to two benzene rings at positions 2-3 and 5-6. It has a role as a ferroptosis inhibitor and a radical scavenger.

General Description

Phenoxazine dyes, including several Nile blue analogs, are known to localize selectively in animal tumors.

Purification Methods

Crystallise phenoxazine from EtOH and sublime it in vacuo. If too impure then extract it in a Soxhlet extractor using toluene. Evaporate the solvent and dissolve the residue (ca 100g) in *C6H6 (1L), CARCINOGEN (use an efficient fume cupboard) and chromatograph it through an Al2O3 column (50 x 450 mm) using *C6H6. The eluent (ca 3L) is evaporated to ca 150mL and cooled when ca 103g of phenoxazine m 149-153o is obtained. Sublimation yields platelets m 158-159o. It forms a green picrate m 141.5-142o. [Gilman & Moore J Am Chem Soc 79 3485 1957, Müller et al. J Org Chem 24 37 1959, Beilstein 27 I 223, 27 III/IV 1209.]

Phenoxazine Preparation Products And Raw materials

Raw materials

Preparation Products

Sulphur Red 6

More

Less

Phenoxazine Suppliers

Americas 1 Austria 1 Belgium 1 Canada 2 China 216 Europe 2 France 1 Germany 6 India 10 Japan 3 Russia 1 South Korea 1 Switzerland 2 Ukraine 2 United Kingdom 8 United States 38 Global 295

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

Alfa Chemistry

Tel
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 24072
Advantage: 58

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 18526
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

AB PharmaTech,LLC

Tel: 323-480-4688
Fax: 323-480-4688
Email: sales@acrospharmatech.com
Country: United States
ProdList: 989
Advantage: 55

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

HBCChem Inc.

Tel: --
Fax: --
Email: sales@hbcchem-inc.com
Country: United States
ProdList: 4569
Advantage: 30

ChemContract Research Inc.

Tel: --
Fax: --
Country: United States
ProdList: 1526
Advantage: 38

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

LOBA FEINCHEMIE GMBH

Tel: --
Fax: --
Email: sales@loba.co.at
Country: United States
ProdList: 72
Advantage: 58

Sarchem Laboratories, Inc.,

Tel: --
Fax: --
Country: United States
ProdList: 349
Advantage: 58

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Anvia Chemicals, LLC

Tel: --
Fax: --
Email: sales@anviachem.com
Country: United States
ProdList: 3933
Advantage: 0

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

Sciencelab.com, Inc.

Tel: --
Fax: --
Email: accounting@sciencelab.com
Country: United States
ProdList: 4159
Advantage: 82

Advance Scientific & Chemical

Tel: --
Fax: --
Email: sales@advance-scientific.com
Country: United States
ProdList: 6419
Advantage: 71

Phentex Corporation

Tel: --
Fax: --
Email: jzhang@phentex.com
Country: United States
ProdList: 11
Advantage: 55

City Chemical LLC

Tel: --
Fax: --
Email: sales@citychemical.com
Country: United States
ProdList: 6708
Advantage: 72

Fisher Scientific

Tel: --
Fax: --
Email: sales@fishersci.com
Country: United States
ProdList: 2337
Advantage: 86

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

City Chemicals Corporation

Tel: --
Fax: --
Country: United States
ProdList: 6460
Advantage: 72

Wilshire Chemical Company Inc.

Tel: --
Fax: --
Email: WilshrChem@AOL.COM
Country: United States
ProdList: 3498
Advantage: 58

More

Less

View Lastest Price from Phenoxazine manufacturers

XINXIANG RUNYU MATERIAL CO., LTD.

Product: Phenoxazine 135-67-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 500kg
Release date: 2021-12-01

Henan Fengda Chemical Co., Ltd

Product: Phenoxazine 135-67-1
Price: US $50.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-22

Henan Aochuang Chemical Co.,Ltd.

Product: Phenoxazine 135-67-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-27

135-67-1, PhenoxazineRelated Search:

PTZ-343 Phenothiazine-10-carbonyl chloride Phenoxazine 1-Hydroxy-5-oxo-5H-pyrido[3,2-]phenoxazine-3-carboxylicaci 4,6-Bis(diphenylphosphino)phenoxazine, NIXANTPHOS ,4,6-Bis(diphenylphosphino)phenoxazine,min.98%NIXANTPHOS,4,6-Bis(diphenylphosphino)phenoxazine, 98+% 3h-phenoxazine,actinomycindderiv 3h-phenoxazine-1,9-dicarboxamide,2-amino-n,n’-bis(hexadecahydro-2,5,9-trimeth sodium 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylate ,1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALT RESORUFIN SODIUM SALT 9-Diethylamino-5-(4,6-dichloro-s-triazinyl)-9H-benzo[a]phenoxazine Chloride 10-ACETYL-PHENOXAZINE-3,7-DIOL DIACETATE 10-ACETYL-3,7-DIHYDROXYPHENOXAZINE 10-DEBC HYDROCHLORIDE 9-DIMETHYLAMINO-5-[4-(16-BUTYL-2,14-DIOXO-3,15-DIOXAEICOSYL)PHENYLIMINO] BENZO[A]PHENOXAZINE 10H-Phenoxazine-3,7-diamine,2-methyl-(9CI) 9-(DIETHYLAMINO)-5-(OCTADECANOYLIMINO)-5H-BENZO[A]PHENOXAZINE 9-dimethylamino-5-[4-(15-butyl-1,13-dioxo-2,14-dioxanonadecyl)phenylimino]benzo[a]phenoxazine 10-ethyl-10H-phenoxazine

Phenoxazine 97%

Phenoxazine >=99%, purified by sublimation

10H-Phenoxazine (9CI)

1H-Phenoxazine

10H-Phenoxazine

5,6-Dibenzo-1,4-oxazine

2,3,5,6-DIBENZO-1,4-OXAZINE

RARECHEM FH 2C 0S92

PHENOXAZINE

PHENAZOXINE

PHENOXAZINE (ELECTRONIC GRADE), 97%

PHENOXAZINE, SUBLIMED, 99+%

Phenoxazine,97%

Phenoxazine, 97% 5GR

Phenoxazine&gt

Phenoxazine, 97%, for synthesis

Phenoxazine ISO 9001：2015 REACH

Phenoxazine (6CI, 7CI, 8CI)

135-67-1

Heterocyclic Building Blocks

Benzoxazines

Building Blocks

Phenylamine Series

Benzoxazines

Building Blocks

Heterocyclic Building Blocks

BenzoxazinesHeterocyclic Building Blocks

N-Containing

Others

organic

Benzothiazoles