SM 324405

Product Name: SM 324405
CAS No.: 677773-91-0
Chemical Name: SM 324405
Synonyms: SM 324405;ODN 20844;SM-324405, 10 mM in DMSO;Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate;methyl {3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate;Methyl 2-(3-((6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)phenyl)acetate;Benzeneacetic acid, 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]-, methyl ester;Inhibitor,Toll-like Receptor (TLR),low toxicity,TLR7,SM-324405,cytokine,diseases,immunotherapy,allergic,SM324405,inhibit
CBNumber: CB73310332
Molecular Formula: C19H23N5O4
Formula Weight: 385.42
MOL File: 677773-91-0.mol

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SM 324405 Property

Melting point:: 246-251 °C
Density: 1.304±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 100 mM
form: A crystalline solid
pka: 10.05±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29457
Product name: SM-324405
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 29457
Product name: SM-324405
Packaging: 25mg
Price: $485
Updated: 2024/03/01

Cayman Chemical

Product number: 29457
Product name: SM-324405
Packaging: 5mg
Price: $127
Updated: 2024/03/01

Cayman Chemical

Product number: 29457
Product name: SM-324405
Packaging: 10mg
Price: $231
Updated: 2024/03/01

Tocris

Product number: 5445
Product name: SM324405
Purity: ≥98%(HPLC)
Packaging: 50
Price: $865
Updated: 2021/12/16

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SM 324405 Chemical Properties,Usage,Production

Uses

SM 324405 is a TLR7 agonist.

in vivo

SM-324405 (9e, intratracheal administration) effectively inhibits allergen-induced airway inflammation without inducing cytokines systemically^[1].
SM-324405 is metabolized to the corresponding acid in human plasma with t_1/2 of 2.6 min^[1]^[2].

IC 50

TLR7: 50 nM (EC₅₀); human TLR7: 7.3 (pEC₅₀); Rat TLR7: 6.6 (pEC₅₀)

storage

Store at +4°C

SM 324405 Preparation Products And Raw materials

Raw materials

Preparation Products

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SM 324405 Suppliers

China 35 United Kingdom 1 United States 4 Global 40

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4769
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1923
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7975
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10343
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 13611835272 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44112
Advantage: 58

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 2955
Advantage: 58

677773-91-0, SM 324405Related Search:

SM 324405

Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate

methyl {3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate

Benzeneacetic acid, 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]-, methyl ester

Inhibitor,Toll-like Receptor (TLR),low toxicity,TLR7,SM-324405,cytokine,diseases,immunotherapy,allergic,SM324405,inhibit

Methyl 2-(3-((6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)phenyl)acetate

ODN 20844

SM-324405, 10 mM in DMSO

677773-91-0