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Ceftobiprole Medocaril Sodium Sterile Powder

Product Name
Ceftobiprole Medocaril Sodium Sterile Powder
CAS No.
252188-71-9
Chemical Name
Ceftobiprole Medocaril Sodium Sterile Powder
Synonyms
BAL5788 sodium;Ceftobiprol medocaril;CEFTOBIPROLE MEDOCARIL SODIUM;Ceftobiprole medocaril sodium;Ceftobiprole Medocaril Sodium Sterile Powder;Sodium (6R,7R)-3-((E)-(1-((R)-1-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)pyrrolidin-3-yl)-2-oxopyrrolidin-3-ylidene)methyl)-7-((Z)-2-(5-amin
CBNumber
CB73311692
Molecular Formula
C26H27N8NaO11S2
Formula Weight
714.66
MOL File
252188-71-9.mol
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Ceftobiprole Medocaril Sodium Sterile Powder Property

storage temp. 
4°C, away from moisture and light
solubility 
DMSO : 250 mg/mL (350.81 mM; Need ultrasonic)
form 
Solid
color 
Off-white to light yellow
InChIKey
UKULSYNDTFCVEY-ATILTDJWNA-N
SMILES
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3=NSC(N)=N3)=N\O)C(=O)N12)/C=C1\CCN([C@@H]2CCN(C(=O)OCC3=C(OC(=O)O3)C)C2)C\1=O)(=O)O.[NaH] |&1:5,7,28,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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Ceftobiprole Medocaril Sodium Sterile Powder Chemical Properties,Usage,Production

Uses

Broad spectrum antibiotic.

in vivo

Ceftobiprole medocaril (s.c.; 3 × q12h; total daily doses of BAL9141 equivalents, 2.1, 4.2, or 8.4 mg/kg) causes ten-day cumulative survival rates ranged from 57 to 100% for female Swiss albino mice (body weight, 20 to 22 g) infected Penr Cros Ctxs strain P-15986[1].
Ceftobiprole medocaril (10, 40, 160 mg/kg; single dose; sc) has T1/2s from 20 min to 31 min, as the dose rose from 40 mg/kg to 160 mg/kg. The AUC/dose values for the escalating single doses ranges from 0.585 to 1.33, and the Cmax/dose values decreases from 1.08 to 0.90 in neutropenic thigh-infected mice[2].

Drug interactions

Potentially hazardous interactions with other drugs
Anticoagulants: effects of coumarins may be enhanced.

Metabolism

Ceftobiprole medocaril sodium is the pro-drug of the active moiety ceftobiprole. Conversion from the prodrug ceftobiprole medocaril sodium, to the active moiety ceftobiprole, occurs rapidly and is mediated by non-specific plasma esterases. Ceftobiprole undergoes minimal metabolism to the open-ring metabolite, which is microbiologically inactive

Ceftobiprole Medocaril Sodium Sterile Powder Preparation Products And Raw materials

Raw materials

Preparation Products

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Ceftobiprole Medocaril Sodium Sterile Powder Suppliers

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252188-71-9, Ceftobiprole Medocaril Sodium Sterile PowderRelated Search:


  • Ceftobiprole Medocaril Sodium Sterile Powder
  • Sodium (6R,7R)-3-((E)-(1-((R)-1-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)pyrrolidin-3-yl)-2-oxopyrrolidin-3-ylidene)methyl)-7-((Z)-2-(5-amin
  • Ceftobiprole medocaril sodium
  • CEFTOBIPROLE MEDOCARIL SODIUM
  • BAL5788 sodium
  • Ceftobiprol medocaril
  • 252188-71-9