(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

Product Name: (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
CAS No.: 1971920-73-6
Chemical Name: (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
Synonyms: PRN-2246;SAR442168;Tolebrutinib;Tolebrutinib, SAR442168;Tolebrutinib/SAR442168/PRN2246;(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-;(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one;Tolebrutinib, (R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one;(R,E)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-(penta-2,4-dien-2-yloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one;2H-Imidazo[4,5-c]pyridin-2-one, 4-amino-1,3-dihydro-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-
CBNumber: CB73336057
Molecular Formula: C26H25N5O3
Formula Weight: 455.51
MOL File: 1971920-73-6.mol

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(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one Property

Boiling point:: 698.1±65.0 °C(Predicted)
Density: 1.334±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (219.53 mM; Need ultrasonic)
pka: 7.03±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0119132
Product name: Tolebrutinib
Purity: 98.96%
Packaging: 5mg
Price: $400
Updated: 2021/12/16

ChemScene

Product number: CS-0119132
Product name: Tolebrutinib
Purity: 98.96%
Packaging: 10mg
Price: $680
Updated: 2021/12/16

ChemScene

Product number: CS-0119132
Product name: Tolebrutinib
Purity: 98.96%
Packaging: 50mg
Price: $1950
Updated: 2021/12/16

ChemScene

Product number: CS-0119132
Product name: Tolebrutinib
Purity: 98.96%
Packaging: 100mg
Price: $2900
Updated: 2021/12/16

Chemenu

Product number: CM330008
Product name: 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]imidazo[4,5-c]pyridin-2-one
Purity: 95%+
Packaging: 1g
Price: $2742
Updated: 2021/12/16

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(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one Chemical Properties,Usage,Production

Uses

Tolebrutinib is a drug candidate; used in preparation of Dihydroimidazopyridine derivatives for treatment of Bruton''s tyrosine kinase related diseases.

(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one Suppliers

China 46 United States 1 Global 47

ShangHai Caerulum Pharma Discovery Co., Ltd.

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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Changzhou Carman Chemical Co., ltd

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View Lastest Price from (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one manufacturers

Henan Fengda Chemical Co., Ltd

Product: (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)- 1971920-73-6
Price: US $8.00-1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

1971920-73-6, (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-oneRelated Search:

(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

PRN-2246

SAR442168

2H-Imidazo[4,5-c]pyridin-2-one, 4-amino-1,3-dihydro-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-

Tolebrutinib

(R,E)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-(penta-2,4-dien-2-yloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

Tolebrutinib, (R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

multiple,PRN 2246,SAR-442168,inhibit,Bruton tyrosine kinase,Tolebrutinib,sclerosis,Bruton,kinase,SAR 442168,tyrosine,Inhibitor,Btk,PRN-2246

Tolebrutinib, SAR442168

(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-

Tolebrutinib/SAR442168/PRN2246

1971920-73-6