ChemicalBook > CAS DataBase List > 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-

1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-

Product Name
1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-
CAS No.
131999-28-5
Chemical Name
1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-
Synonyms
5-HT6/7 antagonist 1;1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-
CBNumber
CB73339553
Molecular Formula
C22H20FN3O3
Formula Weight
393.41
MOL File
131999-28-5.mol
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1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]- Property

Boiling point:
565.6±50.0 °C(Predicted)
Density 
1.346±0.06 g/cm3(Predicted)
pka
7.86±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]- Chemical Properties,Usage,Production

Uses

5-HT6/7 antagonist 1 is a multifunctional ligand that antagonizes 5-HT6/7/2A and D2 receptors, without interacting with M1 receptors and hERG channels.

IC 50

5-HT6 Receptor; 5-HT7 Receptor; 5-HT2A Receptor; D2 Receptor

References

[1] Ko?aczkowski M, et al. Novel arylsulfonamide derivatives with 5-HT?/5-HT? receptor antagonism targeting behavioral and psychological symptoms of dementia. J Med Chem. 2014 Jun 12;57(11):4543-57. DOI:10.1021/jm401895u

1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]- Suppliers

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131999-28-5, 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-Related Search:


  • 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-
  • 5-HT6/7 antagonist 1
  • 131999-28-5