ChemicalBook > CAS DataBase List > Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-

Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-

Product Name
Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
CAS No.
128199-93-9
Chemical Name
Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
Synonyms
5-HT3 antagonist 2;5HT3 antagonist 2,5 HT3 antagonist 2,5-HT-3 antagonist 2;Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
CBNumber
CB73339715
Molecular Formula
C18H21N3O
Formula Weight
295.39
MOL File
128199-93-9.mol
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Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Property

Boiling point:
490.4±35.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
11.29±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Chemical Properties,Usage,Production

Uses

5-HT3 antagonist 2 is a 5-HT3 receptor antagonist.

IC 50

5-HT3 Receptor

References

[1] Swain CJ, et al. Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles). J Med Chem. 1992 Mar 20;35(6):1019-31. DOI:10.1021/jm00084a007

Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- Suppliers

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128199-93-9, Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-Related Search:


  • Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
  • 5-HT3 antagonist 2
  • 5HT3 antagonist 2,5 HT3 antagonist 2,5-HT-3 antagonist 2
  • 128199-93-9