Tubulysin B

Product Name: Tubulysin B
CAS No.: 205304-87-6
Chemical Name: Tubulysin B
Synonyms: Tubulysin B;(2S,4R)-4-({2-[(1R,3R)-1-(acetyloxy)-3-[(2S,3S)-N-[(butanoyloxy)methyl]-3-methyl-2-{[(2R)-1-methylpiperidin-2-yl]formamido}pentanamido]-4-methylpentyl]-1,3-thiazol-4-yl}formamido)-5-(4-hydroxyphenyl)-2-methylpentanoic acid;Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-
CBNumber: CB73339922
Molecular Formula: C42H63N5O10S
Formula Weight: 830.05
MOL File: 205304-87-6.mol

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Tubulysin B Property

Boiling point:: 978.0±65.0 °C(Predicted)
Density: 1.204±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 4.52±0.23(Predicted)
color: White to off-white
InChIKey: HWCIETDQUHYHGQ-OSGLCLOFNA-N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC11284
Product name: TubulysinB
Purity: >98%
Packaging: 1mg
Price: $1200
Updated: 2021/12/16

DC Chemicals

Product number: DC11284
Product name: TubulysinB
Purity: >98%
Packaging: 5mg
Price: $3600
Updated: 2021/12/16

DC Chemicals

Product number: DC11284
Product name: TubulysinB
Purity: >98%
Packaging: 10mg
Price: $6500
Updated: 2021/12/16

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Tubulysin B Chemical Properties,Usage,Production

Description

Tubulysin B is a highly cytotoxic peptide and potent microtubule destabilizing agent isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin B has IC50 values in the picomolar range against many cancer cell lines, including those with multidrug-resistant properties. It is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.

Definition

ChEBI: Tubulysin B is a butyrate ester.

in vitro

Tubulysin B has IC50s of 0.6 and 0.9 nM against KB and A549 tumors cell lines, respectively.

Tubulysin B Preparation Products And Raw materials

Raw materials

Preparation Products

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Tubulysin B Suppliers

China 12 India 1 United States 2 Global 15

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4577
Advantage: 55

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3254
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1990
Advantage: 58

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Tianjin Shangde Medicine Edge Technology Co., Ltd

Tel: 13370460931
Email: sales@accendatech.com
Country: China
ProdList: 11
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Hangzhou FuRun Pharmaceutical Technology Co., Ltd

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Email: 1900830611@qq.com
Country: China
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Jiangxi ravel Biotechnology Co.,Ltd

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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9962
Advantage: 58

205304-87-6, Tubulysin BRelated Search:

Tubulysin B

Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-

(2S,4R)-4-({2-[(1R,3R)-1-(acetyloxy)-3-[(2S,3S)-N-[(butanoyloxy)methyl]-3-methyl-2-{[(2R)-1-methylpiperidin-2-yl]formamido}pentanamido]-4-methylpentyl]-1,3-thiazol-4-yl}formamido)-5-(4-hydroxyphenyl)-2-methylpentanoic acid

205304-87-6

C42H63N5O10S