ChemicalBook > CAS DataBase List > H2N-PEG6-CH2COOtBu

H2N-PEG6-CH2COOtBu

Product Name
H2N-PEG6-CH2COOtBu
CAS No.
297162-50-6
Chemical Name
H2N-PEG6-CH2COOtBu
Synonyms
NH2-PEG6-C1-Boc;H2N-PEG6-CH2COOtBu;NH2-PEG6-CH2COOtBu;NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu;tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc;tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate;H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
CBNumber
CB73340573
Molecular Formula
C18H37NO8
Formula Weight
395.48828
MOL File
297162-50-6.mol
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H2N-PEG6-CH2COOtBu Property

Boiling point:
463.4±40.0 °C(Predicted)
Density 
1.065±0.06 g/cm3(Predicted)
pka
8.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
250mg
Price
$256
Updated
2021/12/16
Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
1g
Price
$583
Updated
2021/12/16
Activate Scientific
Product number
AS104025
Product name
H2N-PEG6-CH2COOtBu
Purity
95+%
Packaging
5G
Price
$1478
Updated
2021/12/16
Acrotein
Product number
B-0891
Product name
H2N-PEG6-CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$302.5
Updated
2021/12/16
purepeg
Product number
4328206
Product name
H2N-PEG6-CH2COOtBu
Purity
min.97%
Packaging
1g
Price
$450
Updated
2021/12/16
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H2N-PEG6-CH2COOtBu Chemical Properties,Usage,Production

Biological Activity

NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

H2N-PEG6-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG6-CH2COOtBu Suppliers

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297162-50-6, H2N-PEG6-CH2COOtBuRelated Search:


  • H2N-PEG6-CH2COOtBu
  • NH2-PEG6-C1-Boc
  • NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu
  • NH2-PEG6-CH2COOtBu
  • tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate
  • NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc
  • H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
  • 3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
  • tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate
  • 297162-50-6