p38-α MAPK-IN-1

Product Name: p38-α MAPK-IN-1
CAS No.: 443913-15-3
Chemical Name: p38-α MAPK-IN-1
Synonyms: MAPK-IN-1;p38-α MAPK-IN-1;MAPK14 INHIBITOR;p38-α MAPK inhibitor 1;p38-α MAPK-IN-1 ，E2372;p38-α MAPK-IN-1, 10 mM in DMSO;Inhibitor,inhibit,p-38-α MAPK-IN-1,Autophagy,p38α MAPKIN1,p38 MAPK,p38 α MAPK IN 1;1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)phenyl)urea;Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]phenyl]-
CBNumber: CB73356169
Molecular Formula: C27H35N5O3
Formula Weight: 477.6
MOL File: 443913-15-3.mol

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p38-α MAPK-IN-1 Property

Boiling point:: 566.2±50.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 100 mg/mL (209.38 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 13.76±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7765
Product name: p38-αMAPK-IN-1
Purity: 99.90%
Packaging: 1mg
Price: $132
Updated: 2021/12/16

ChemScene

Product number: CS-7765
Product name: p38-αMAPK-IN-1
Purity: 99.90%
Packaging: 5mg
Price: $396
Updated: 2021/12/16

ChemScene

Product number: CS-7765
Product name: p38-αMAPK-IN-1
Purity: 99.90%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-7765
Product name: p38-αMAPK-IN-1
Purity: 99.90%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

ChemScene

Product number: CS-7765
Product name: p38-αMAPK-IN-1
Purity: 99.90%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

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p38-α MAPK-IN-1 Chemical Properties,Usage,Production

Uses

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

References

[1] Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67. DOI:10.1021/jm901297e

p38-α MAPK-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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443913-15-3, p38-α MAPK-IN-1Related Search:

p38-α MAPK inhibitor 1

MAPK-IN-1

MAPK14 INHIBITOR

Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]phenyl]-

p38-α MAPK-IN-1

Inhibitor,inhibit,p-38-α MAPK-IN-1,Autophagy,p38α MAPKIN1,p38 MAPK,p38 α MAPK IN 1

1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)phenyl)urea

p38-α MAPK-IN-1, 10 mM in DMSO

p38-α MAPK-IN-1 ，E2372

443913-15-3