m-PEG3-4-nitrophenyl carbonate

Product Name: m-PEG3-4-nitrophenyl carbonate
CAS No.: 105108-59-6
Chemical Name: m-PEG3-4-nitrophenyl carbonate
Synonyms: m-PEG2-4-nitrophenyl carbonate;m-PEG3-4-nitrophenyl carbonate;2-(2-methoxyethoxy)ethyl (4-nitrophenyl) carbonate;Carbonic acid, 2-(2-methoxyethoxy)ethyl 4-nitrophenyl ester
CBNumber: CB73363954
Molecular Formula: C12H15NO7
Formula Weight: 285.25
MOL File: 105108-59-6.mol

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m-PEG3-4-nitrophenyl carbonate Property

Boiling point:: 414.3±45.0 °C(Predicted)
Density: 1.273±0.06 g/cm3(Predicted)
form: Liquid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23305
Product name: m-PEG3-4-nitrophenylcarbonate
Purity: 96%
Packaging: 250mg
Price: $360
Updated: 2021/12/16

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m-PEG3-4-nitrophenyl carbonate Chemical Properties,Usage,Production

Description

m-PEG3-4-nitrophenyl carbonate is a PEG linker with a nitrophenyl carbonate moiety. NPC is reactive towards the amino group of lysine by means of stable urethane linkages. The hydrophilic PEG linker increases the water solubility of the compound.

Uses

m-PEG2-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

m-PEG3-4-nitrophenyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG3-4-nitrophenyl carbonate Suppliers

China 15 United States 2 Global 17

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105108-59-6, m-PEG3-4-nitrophenyl carbonateRelated Search:

m-PEG3-4-nitrophenyl carbonate

m-PEG2-4-nitrophenyl carbonate

2-(2-methoxyethoxy)ethyl (4-nitrophenyl) carbonate

Carbonic acid, 2-(2-methoxyethoxy)ethyl 4-nitrophenyl ester

105108-59-6