Prolyl Endopeptidase Inhibitor II

Product Name: Prolyl Endopeptidase Inhibitor II
CAS No.: 108708-25-4
Chemical Name: Prolyl Endopeptidase Inhibitor II
Synonyms: 1-Pyrrolidinecarboxylic acid, 2-[(2-formyl-1-pyrrolidinyl)carbonyl]-, phenylmethyl ester
CBNumber: CB73364395
Molecular Formula: C18H22N2O4
Formula Weight: 330.38
MOL File: 108708-25-4.mol

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Prolyl Endopeptidase Inhibitor II Property

Boiling point:: 529.1±50.0 °C(Predicted)
Density: 1.312±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: 10mg/mL
DMF: soluble
ethyl acetate: soluble
pka: -2.43±0.40(Predicted)
form: oil
color: colorless to off-white
Sequence: Z-Pro-Pro-CHO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 537011
Product name: Prolyl Endopeptidase Inhibitor II - CAS 108708-25-4 - Calbiochem
Packaging: 5mg
Price: $303
Updated: 2024/03/01

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Prolyl Endopeptidase Inhibitor II Chemical Properties,Usage,Production

Uses

Z-Pro-Pro-CHO is a prolyl oligopeptidase inhibitor (IC50: 0.16 μM and 0.01 μM for human and Schistosoma Mansoni prolyl oligopeptidase respectively)[1].

Biological Activity

Cell permeable: yes', 'Primary Target
Mouse brain prolylendooeotidase', 'Product does not compete with ATP.', 'Reversible: no', 'Target Ki: 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively

IC 50

Schistosome

References

[1] Fajtová P, et al. Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors. PLoS Negl Trop Dis. 2015 Jun 3;9(6):e0003827. DOI:10.1371/journal.pntd.0003827

Prolyl Endopeptidase Inhibitor II Preparation Products And Raw materials

Raw materials

Preparation Products

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Prolyl Endopeptidase Inhibitor II Suppliers

China 6 United States 1 Global 7

Nanjing Leon Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Hangzhou Sinoda Pharmaceutical Technology Co. LTD

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Merck KGaA

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LEON (NANJING) BIOTECHNOLOGY CO., LTD.

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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
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108708-25-4, Prolyl Endopeptidase Inhibitor IIRelated Search:

1-Pyrrolidinecarboxylic acid, 2-[(2-formyl-1-pyrrolidinyl)carbonyl]-, phenylmethyl ester

108708-25-4