ChemicalBook > CAS DataBase List > Desidustat

Desidustat

Product Name: Desidustat
CAS No.: 1616690-16-4
Chemical Name: Desidustat
Synonyms: ZYAN1;ZYAN 1;CS-2813;Desidustat;Desidustat (ZYAN1, ZYAN1-1001);(1-(Cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine;Glycine, N-[[1-(cyclopropylmethoxy)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-;Desidustat【(1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine】;ischemia,hypoxia,inhibit,HIF-PH,Desidustat,anemia,Inhibitor,HIF hydroxylase,HIF/HIF Prolyl-Hydroxylase,Hypoxia-inducible factors,disorders,HIFs
CBNumber: CB73373063
Molecular Formula: C16H16N2O6
Formula Weight: 332.31
MOL File: 1616690-16-4.mol

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Desidustat Property

Melting point:: 212-214°C
Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 3.61±0.10(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28074
Product name: Desidustat
Packaging: 50mg
Price: $507
Updated: 2024/03/01

Cayman Chemical

Product number: 28074
Product name: Desidustat
Packaging: 100mg
Price: $723
Updated: 2024/03/01

Cayman Chemical

Product number: 28074
Product name: Desidustat
Packaging: 10mg
Price: $145
Updated: 2024/03/01

TRC

Product number: D297695
Product name: Desidustat
Packaging: 100mg
Price: $675
Updated: 2021/12/16

AK Scientific

Product number: 8550DX
Product name: Desidustat
Packaging: 10mg
Price: $260
Updated: 2021/12/16

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Desidustat Chemical Properties,Usage,Production

Uses

Desidustat, is an HIF hydroxylase inhibitor.

in vivo

Desidustat (oral; 10-100 mg/kg) has good efficacy in vivo^[1].

Animal Model:	C57 Mice^[1]
Dosage:	10, 30, 50, 100 mg/kg; 20 mg /kg
Administration:	oral gavage; oral, once, daily, for 7 days
Result:	Significant increased the level of EPO and Hb.

Desidustat Preparation Products And Raw materials

Raw materials

Preparation Products

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1616690-16-4, DesidustatRelated Search:

Desidustat

ZYAN 1

ZYAN1

CS-2813

Desidustat【(1-(cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine】

Glycine, N-[[1-(cyclopropylmethoxy)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]-

ischemia,hypoxia,inhibit,HIF-PH,Desidustat,anemia,Inhibitor,HIF hydroxylase,HIF/HIF Prolyl-Hydroxylase,Hypoxia-inducible factors,disorders,HIFs

(1-(Cyclopropylmethoxy)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine

Desidustat (ZYAN1, ZYAN1-1001)

1616690-16-4