DSPE-PEG5-azide
- Product Name
- DSPE-PEG5-azide
- CAS No.
- 2112737-73-0
- Chemical Name
- DSPE-PEG5-azide
- Synonyms
- DSPE-PEG5-N3;DSPE-PEG5-azide;DSPE-PEG5-azide,DSPE-PEG5-N3
- CBNumber
- CB73373614
- Molecular Formula
- C54H105N4O14P
- Formula Weight
- 1065.42
- MOL File
- 2112737-73-0.mol
DSPE-PEG5-azide Property
- storage temp.
- -20°C, protect from light
- solubility
- Soluble in DCM
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- BP-23652
- Product name
- DSPE-PEG5-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $860
- Updated
- 2021/12/16
DSPE-PEG5-azide Chemical Properties,Usage,Production
Description
DSPE-PEG5-azide is a heterobifunctional PEG linker. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN.
Uses
DSPE-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DSPE-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DSPE-PEG5-azide Preparation Products And Raw materials
Raw materials
Preparation Products
DSPE-PEG5-azide Suppliers
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 20405
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
View Lastest Price from DSPE-PEG5-azide manufacturers
- Product
- DSPE-PEG5-azide 2112737-73-0
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-30