ChemicalBook > CAS DataBase List > CIL56

CIL56

Product Name
CIL56
CAS No.
300802-28-2
Chemical Name
CIL56
Synonyms
CA3;CIL56;CA3 NEW;CIL56(CA3);CA3 (CIL-56);YAP1 inhibitor CA3;CIL56, 10 mM in DMSO;CIL56;CIL-56;CIL 56;CA3;CA-3;CA 3;Recombinant Human CA3 Protein, His Tag;Inhibitor,CIL 56,inhibit,Ferroptosis,CIL56,CIL-56
CBNumber
CB73376842
Molecular Formula
C23H27N3O5S2
Formula Weight
489.61
MOL File
300802-28-2.mol
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CIL56 Property

Boiling point:
741.7±70.0 °C(Predicted)
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 0.15 mg/ml
form 
A crystalline solid
pka
10.16±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2647
Product name
CA3
Purity
≥97% (HPLC)
Packaging
5mg
Price
$105
Updated
2025/07/31
Sigma-Aldrich
Product number
SML2647
Product name
CA3
Purity
≥97% (HPLC)
Packaging
25mg
Price
$406
Updated
2025/07/31
Cayman Chemical
Product number
19287
Product name
CIL56
Purity
≥95%
Packaging
1mg
Price
$28
Updated
2024/03/01
Cayman Chemical
Product number
19287
Product name
CIL56
Purity
≥95%
Packaging
5mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
19287
Product name
CIL56
Purity
≥95%
Packaging
10mg
Price
$152
Updated
2024/03/01
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CIL56 Chemical Properties,Usage,Production

Uses

CIL56 inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS.

Biological Activity

CA3 is a potent and selective inhibitor of YAP1 (Hippo co-activator Yes-associated protein 1) th at inhibits YAP1 expression and transcriptional activity in esophageal adenocarcinoma (EAC) cell lines. CA3 potently inhibits growth, induces apoptosis in radiation resistant CSC (cancer stem cell) enriched EAC cells. It inhibits tumor growth of in xenograft model with no apparent toxicity.

CIL56 Preparation Products And Raw materials

Raw materials

Preparation Products

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CIL56 Suppliers

China 78 India 1 United Kingdom 1 United States 6 Global 86
Guangzhou Isun Pharmaceutical Co., Ltd
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View Lastest Price from CIL56 manufacturers

Career Henan Chemical Co
Product
CIL56 300802-28-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

300802-28-2, CIL56Related Search:


  • CIL56
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  • N-[2;7-BIS(PIPERIDIN-1-YLSULFONYL)FLUOREN-9-YLIDENE]HYDROXYLAMINE;CA3;CIL 56;CIL-56
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  • N-Hydroxy-2,7-bis(1-piperidinylsulfonyl)-9H-fluoren-9-imine
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  • CIL56;CIL-56;CIL 56;CA3;CA-3;CA 3
  • 9H-Fluoren-9-one, 2,7-bis(1-piperidinylsulfonyl)-, oxime
  • Recombinant Human CA3 Protein, His Tag
  • CA3 (CIL-56)
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  • 2,7-Bis(piperidin-1-ylsulfonyl)-9H-fluoren-9-one oxime
  • Inhibitor,CIL 56,inhibit,Ferroptosis,CIL56,CIL-56
  • CIL56, 10 mM in DMSO
  • 300802-28-2