3,5-Dichlorobenzonitrile
- Product Name
- 3,5-Dichlorobenzonitrile
- CAS No.
- 6575-00-4
- Chemical Name
- 3,5-Dichlorobenzonitrile
- Synonyms
- 3,5-Dichlorobenzonit;3,5-DICHLOROBENZONITRILE;3,5-dichlorobenzenenitrile;3,5-Dichlorobenzonitrile>Benzonitrile, 3,5-dichloro-;3,5-Dichlorobenzonitrile 97%;3,5-Dichlorobenzonitrile,97%;13C6]-3,5-Dichlorobenzonitrile;3,5-Dichlorobenzenecarbonitrile;6-chloro-1,3-diethylpyrimidine-2,4-dione
- CBNumber
- CB7344152
- Molecular Formula
- C7H3Cl2N
- Formula Weight
- 172.01
- MOL File
- 6575-00-4.mol
3,5-Dichlorobenzonitrile Property
- Melting point:
- 64-66 °C (lit.)
- Boiling point:
- 283.76°C (rough estimate)
- Density
- 1.4980 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform, Methanol (Slightly)
- form
- Crystalline Powder
- color
- White to beige-brownish
- BRN
- 2207019
- InChI
- InChI=1S/C7H3Cl2N/c8-6-1-5(4-10)2-7(9)3-6/h1-3H
- InChIKey
- PUJSUOGJGIECFQ-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC(Cl)=CC(Cl)=C1
- CAS DataBase Reference
- 6575-00-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 3,5-Dichlorobenzonitrile(6575-00-4)
Safety
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-37/39-36/37/39-22-36-36/37-9
- RIDADR
- 3276
- WGK Germany
- 3
- Hazard Note
- Irritant/Toxic
- TSCA
- N
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 139394
- Product name
- 3,5-Dichlorobenzonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $53.1
- Updated
- 2023/01/07
- Product number
- D3261
- Product name
- 3,5-Dichlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $38
- Updated
- 2025/07/31
- Product number
- D3261
- Product name
- 3,5-Dichlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $113
- Updated
- 2025/07/31
- Product number
- D436528
- Product name
- 3,5-Dichlorobenzonitrile
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 3637-5-Z0
- Product name
- 3,5-Dichlorobenzonitrile
- Packaging
- 25g
- Price
- $104
- Updated
- 2021/12/16
3,5-Dichlorobenzonitrile Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
3,5-Dichlorobenzonitrile was used as internal standard during the programmed temperature vaporization-GC-MS determination of dichlobenil and 2,6-dichlorobenzamide in onions.
Synthesis
19752-55-7
6575-00-4
General procedure for the synthesis of 3,5-dichlorobenzonitrile from 3,5-dichloro-1-bromobenzene: iPrMgCl (2M in THF, 4.1 mL) and THF (5 mL) were added to a flask containing dry LiCl (0.35 g, 8.24 mmol) at 15 °C. After stirring for 15 min, a solution of 3,5-dichloro-1-bromobenzene (1.46 g, 8.03 mmol) in THF (1 mL) was slowly added to the reaction mixture and stirring was continued for 15 min. Subsequently, the reaction mixture was cooled to 0 °C, DMF (1.3 mL, 12 mmol) was added and stirred at this temperature for 2 hours. Upon completion of the reaction, aqueous NH3 (7 mL, 28-30%) and I2 (4.06 g, 16 mmol) were sequentially added to the mixture. After stirring for 2 h at room temperature, the reaction mixture was poured into saturated aqueous Na2SO3 solution and extracted with CHCl3 (3 x 30 mL). The organic layers were combined, dried with Na2SO4 and filtered. After removing the solvent under reduced pressure, the residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 9:1, v/v) to afford pure 3,5-dichlorobenzonitrile (0.73 g) in 71% yield. Most of the nitrile compounds involved in this study were commercially available and were identified by comparison with real samples.
References
[1] Tetrahedron, 2013, vol. 69, # 5, p. 1462 - 1469
3,5-Dichlorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dichlorobenzonitrile manufacturers
- Product
- 3,5-Dichlorobenzonitrile 6575-00-4
- Price
- US $30.00-10.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100000kg
- Release date
- 2024-08-20
- Product
- 3,5-Dichlorobenzonitrile 6575-00-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24