ChemicalBook > CAS DataBase List > 1,2-DIAMINO-3,5-DIFLUOROBENZENE

1,2-DIAMINO-3,5-DIFLUOROBENZENE

Product Name
1,2-DIAMINO-3,5-DIFLUOROBENZENE
CAS No.
2369-29-1
Chemical Name
1,2-DIAMINO-3,5-DIFLUOROBENZENE
Synonyms
3,5-Difluorobenzene-1,2-diamine;BUTTPARK 19\01-53;1,2-DIAMINO-3,5-DIFLUOROBENZENE;3,5-DIFLUORO-1,2-PHENYLENEDIAMINE;1,2-Benzenediamine, 3,5-difluoro-;3,5-Difluorophenylene-1,2-diamine, 1,2-Diamino-3,5-difluorobenzene
CBNumber
CB7347269
Molecular Formula
C6H6F2N2
Formula Weight
144.12
MOL File
2369-29-1.mol
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1,2-DIAMINO-3,5-DIFLUOROBENZENE Property

Melting point:
48.5-49.5℃
Boiling point:
246.1±35.0 °C(Predicted)
Density 
1.407±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
crystalline solid
pka
2.83±0.10(Predicted)
color 
White to dark brown two-tone
CAS DataBase Reference
2369-29-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2921599090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS010697
Product name
1,2-diamino-3,5-difluorobenzene
Purity
AldrichCPR
Packaging
250MG
Price
$73.1
Updated
2025/07/31
TRC
Product number
D442345
Product name
3,5-Difluorobenzene-1,2-diamine
Packaging
1g
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
PC0143
Product name
3,5-Difluorobenzene-1,2-diamine
Packaging
1g
Price
$22
Updated
2021/12/16
Matrix Scientific
Product number
007008
Product name
1,2-Diamino-3,5-difluorobenzene
Purity
98%
Packaging
1g
Price
$23
Updated
2021/12/16
AK Scientific
Product number
1630AB
Product name
3,5-Difluorobenzene-1,2-diamine
Packaging
1g
Price
$27
Updated
2021/12/16
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1,2-DIAMINO-3,5-DIFLUOROBENZENE Chemical Properties,Usage,Production

Synthesis

364-30-7

2369-29-1

General procedure for the synthesis of 3,5-difluoro-1,2-phenylenediamine from 2,4-difluoro-6-nitroaniline: concentrated hydrochloric acid (10 mL) was slowly added dropwise to a mixture of 2,4-difluoro-6-nitroaniline (1.6 g, 9 mmol) and tin powder (22.5 mmol). The reaction mixture was heated to reflux for 1.5 h, subsequently cooled to room temperature and neutralized with 50% NaOH solution to pH 9-10. The precipitate was collected by filtration, dried and extracted with hot ethyl acetate (80 mL). The filtrate was subjected to secondary evaporation to give 3,5-difluoro-1,2-benzenediamine. Yield: 0.60 g (46%); the product was brown crystals; melting point 55-57 °C; Rf value was 0.86.

References

[1] Tetrahedron Letters, 2006, vol. 47, # 27, p. 4591 - 4595
[2] European Journal of Medicinal Chemistry, 2009, vol. 44, # 7, p. 2930 - 2935
[3] Synthesis (Germany), 2016, vol. 48, # 3, p. 394 - 406
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 153
[5] Journal of the American Chemical Society, 1959, vol. 81, p. 94,98

1,2-DIAMINO-3,5-DIFLUOROBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-DIAMINO-3,5-DIFLUOROBENZENE Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
A.J Chemicals
Tel
--
Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
SL Drugs and Pharmaceuticals Pvt. Ltd.
Tel
--
Fax
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Email
enquiry@sldrugs.com
Country
India
ProdList
2683
Advantage
50
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View Lastest Price from 1,2-DIAMINO-3,5-DIFLUOROBENZENE manufacturers

Career Henan Chemical Co
Product
1,2-DIAMINO-3,5-DIFLUOROBENZENE 2369-29-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11