METHYL 5,6-DICHLORONICOTINATE
- Product Name
- METHYL 5,6-DICHLORONICOTINATE
- CAS No.
- 56055-54-0
- Chemical Name
- METHYL 5,6-DICHLORONICOTINATE
- Synonyms
- 3W-0272;ZINC00168870;5,6-dichloro-methyl ester;METHYL 5,6-DICHLORONICOTINATE;Methyl 5,6-dichloronicotinate 97%;Methyl 5,6-dichloropyridine-3-carboxylate;5,6-dichloro-3-pyridinecarboxylic acid methyl ester;3-pyridinecarboxylic acid, 5,6-dichloro-, methyl ester;Methyl 5,6-dichloropyridine-3-carboxylate, 2,3-Dichloro-5-(methoxycarbonyl)pyridine;Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine
- CBNumber
- CB7347496
- Molecular Formula
- C7H5Cl2NO2
- Formula Weight
- 206.03
- MOL File
- 56055-54-0.mol
METHYL 5,6-DICHLORONICOTINATE Property
- Melting point:
- 63-65°C
- Boiling point:
- 265.5±35.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -2.84±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M301393
- Product name
- Methyl5,6-dichloronicotinate
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 044285
- Product name
- Methyl 5,6-dichloronicotinate
- Purity
- >95%
- Packaging
- 5g
- Price
- $59
- Updated
- 2021/12/16
- Product number
- 4H23-5-Y0
- Product name
- Methyl 5,6-dichloronicotinate
- Packaging
- 5G
- Price
- $152
- Updated
- 2021/12/16
- Product number
- 4H23-5-Y0
- Product name
- Methyl 5,6-dichloronicotinate
- Packaging
- 25g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- Y9471
- Product name
- Methyl5,6-dichloropyridine-3-carboxylate
- Packaging
- 100g
- Price
- $711
- Updated
- 2021/12/16
METHYL 5,6-DICHLORONICOTINATE Chemical Properties,Usage,Production
Synthesis
67-56-1
41667-95-2
56055-54-0
1. 5,6-Dichloropyridine-3-carboxylic acid (5 g) and thionyl chloride (3.10 g) were dissolved in methanol (20 mL) and the reaction was stirred overnight at 25 °C. 2. Upon completion of the reaction, cold water (100 mL) was added to the mixture and the mixture was neutralized with saturated sodium bicarbonate solution to pH neutral. 3. The aqueous layer was extracted using dichloromethane (2 x 100 mL). 4. The organic layers were combined, dried with anhydrous sodium sulfate and filtered to remove the drying agent. 5. The filtrate was concentrated under reduced pressure to give 5,6-dichloronicotinic acid methyl ester (5 g) as a white solid. 6. dried with anhydrous sodium sulfate and filtered to remove the desiccant. 5. The filtrate was concentrated under reduced pressure to give methyl 5,6-dichloronicotinate (5 g) as a white solid. 6. Mass Spectrometry (ESI): theoretical value of 205 for C7H5Cl2NO2; measured 206 [M + H]. 7.
References
[1] Patent: WO2008/7900, 2008, A1. Location in patent: Page/Page column 15; 26
[2] Patent: US2009/209540, 2009, A1. Location in patent: Page/Page column 15; 7
[3] Patent: WO2008/128968, 2008, A1. Location in patent: Page/Page column 51
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 12, p. 3719 - 3742
[5] Patent: WO2018/165385, 2018, A1. Location in patent: Paragraph 00391
METHYL 5,6-DICHLORONICOTINATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 5,6-DICHLORONICOTINATE manufacturers
- Product
- METHYL 5,6-DICHLORONICOTINATE 56055-54-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-04
- Product
- METHYL 5,6-DICHLORONICOTINATE 56055-54-0
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- Methyl 5,6-Dichloronicotinate 56055-54-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10