(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)

Product Name: (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
CAS No.: 186142-28-9
Chemical Name: (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)
Synonyms: SEVNLDAEFR;H-Ser-Glu-Val-Asn;β-Secretase SubstrateⅡ;BETA-SECRETASE SUBSTRATE II;[ASN670, LEU671]AMYLOID-BETA;(ASN670,LEU671)-APP770 (667-676);A4 PROTEIN PRECURSOR770 (667-676);SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG;H-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-OH;(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR 7
CBNumber: CB7349526
Molecular Formula: C50H78N14O19
Formula Weight: 1179.24
MOL File: 186142-28-9.mol

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(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Property

storage temp.: -20°C
form: solid
Sequence: Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A1972
Product name: [Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt
Purity: ≥95% (HPLC)
Packaging: 1mg
Price: $156
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FA109374
Product name: (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt
Packaging: 5mg
Price: $183
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109374
Product name: (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt
Packaging: 10mg
Price: $311
Updated: 2021/12/16

AK Scientific

Product number: 3870CR
Product name: (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(1S)-1-carboxy-4-(diaminomethylideneamino)butyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoicacid
Packaging: 10mg
Price: $469
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109374
Product name: (Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt
Packaging: 25mg
Price: $622
Updated: 2021/12/16

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(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Chemical Properties,Usage,Production

Uses

SEVNLDAEFR is a substrate for BACE1[1].

Biochem/physiol Actions

Substrate for assaying β-secretase activity that corresponds to the "Swedish" Lys-Met/Asn-Leu mutation of the amyloid precursor protein β-secretase cleavage site.

References

[1] Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448. DOI:10.1007/s00216-018-1354-6

(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) Preparation Products And Raw materials

Raw materials

Preparation Products

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186142-28-9, (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)Related Search:

AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) MCA-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)-LYS(DNP)-ARG-ARG AMIDE LYS(DABSYL)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)-GLN-LUCIFER YELLOW (ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG TRIFLUOROACETATE SALT

(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt

A4 PROTEIN PRECURSOR770 (667-676)

SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG

SEVNLDAEFR

(ASN670,LEU671)-APP770 (667-676)

(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676)

[ASN670, LEU671]AMYLOID-BETA

BETA-SECRETASE SUBSTRATE II

H-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-OH

(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR 7

[asn670, leu671]-amyloid β/a4 precursor protein 770 fragment 667-676 trifluoroacetate salt

H-Ser-Glu-Val-Asn

β-Secretase SubstrateⅡ

[Asn670,Leu671]-Amyloid β/A4 Protein Precursor770 (667-676)

(Asn670,Leu671)-APP770 (667-676), APP770 (667-676) Swedish Mutation

(Asn???,Leu6?1)-Amyloid β/A4 Protein Precursor??? (667-676)

L-Arginine, L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-

Asn670, Leu671]-Amyloid beta/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt

Asn670, Leu671]-Amyloid beta/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt >=95% (HPLC), solid

(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (667-676) USP/EP/BP

(Asn,Leu61)-Amyloid β/A4 Protein Precursor (667-676)

(Asn???,Leu??1)-Amyloid β/A4 Protein Precursor??? (667-676) trifluoroacetate salt

(Asn???,Leu???)-Amyloid β/A4 Protein Precursor??? (667-676) trifluoroacetate salt

[Asn<sup>670</sup>, Leu<sup>671</sup>]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt

186142-28-9

C50H78N14O19

Enzyme Substrates

Enzymes, Inhibitors, and Substrates

Substrates by Enzyme

BioChemical

Biochemicals and Reagents

beta-Secretase

Amyloid Precursor ProteinsEnzyme Substrates

beta-SecretaseEnzyme Substrates

beta-SecretaseNeuropeptides

Other Amyloid Protein Fragments

Alzheimers and Neurodegenerative Disease Research

Neurodegenerative Disease Peptides

Protease Substrates

Substrates by Enzyme

β Amyloid Peptides