ChemicalBook > CAS DataBase List > 7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol
7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol
- Product Name
- 7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol
- CAS No.
- 446826-86-4
- Chemical Name
- 7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol
- Synonyms
- KIN-1400;KIN-1400 (KIN1400;KIN1400 >=98% (HPLC);7-[(2-benzothiazolylamino)[4-(difluoromethoxy)phenyl]methyl]-8-quinolinol;8-Quinolinol, 7-[(2-benzothiazolylamino)[4-(difluoromethoxy)phenyl]methyl]-;7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol;7-[(1,3-benzothiazol-2-ylamino)-[4-(difluoromethoxy)phenyl]methyl]quinolin-8-ol
- CBNumber
- CB73582663
- Molecular Formula
- C24H17F2N3O2S
- Formula Weight
- 449.47
- MOL File
- 446826-86-4.mol
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7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol Property
- Boiling point:
- 651.1±65.0 °C(Predicted)
- Density
- 1.443±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO:30.0(Max Conc. mg/mL);66.74(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.67(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);4.45(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);66.74(Max Conc. mM) - form
- powder
- pka
- 4.23±0.50(Predicted)
- color
- white to beige
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1871
- Product name
- KIN1400
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $105
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML1871
- Product name
- KIN1400
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $424
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22441
- Product name
- KIN1400
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $43
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22441
- Product name
- KIN1400
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $95
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22441
- Product name
- KIN1400
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $167
- Updated
- 2024/03/01
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7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol Chemical Properties,Usage,Production
Biological Activity
KIN1400 is innate immune agonists of IRF3 activation th at induces IRF3 and MAVS dependent innate immune antiviral genes and IFNβ expression. KIN1400 is a broad spectrum antiviral compound th at suppresses replication of hepatitis C virus, West Nile virus, dengue virus and other Flaviviridae, as well as Filoviridae (EV), Orthomyxoviridae (influenza A virus), Arenaviridae (LV) and Paramyxoviridae (RCV, NV).
7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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7-((benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol Suppliers
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