1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE

Product Name: 1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE
CAS No.: 167710-87-4
Chemical Name: 1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE
Synonyms: RS 39604;RS39604HCl;RS 39604 HYDROCHLORIDE;1-(4-Amino-5-Chloro-2-(3,5-Dimethoxyphenyl)Methyloxy)-3-(1-(2-Methylsulfonylamino)Ethyl)Piperidin-4-;1-(4-Amino-5-chloro-2-(3,5-dimethoxyphenyl)methyloxy)-3-(1-(2-methylsulfonylamino)ethyl)piperidin-4-yl)propan-1-onehyd;1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE;1-[4-Amino-5-Chloro-2-(3,5-Dimethoxyphenyl)Methyloxy]-3-[[1-[2-Methylsulphonylamino]Ethyl]Piperidin-4-Yl]Propan-1-One Hydrochloride
CBNumber: CB7368000
Molecular Formula: C26H37Cl2N3O6S
Formula Weight: 590.56
MOL File: 167710-87-4.mol

More

Less

1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE Property

storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO
form: Powder
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 0991
Product name: RS39604hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $176
Updated: 2021/12/16

Tocris

Product number: 0991
Product name: RS39604hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $744
Updated: 2021/12/16

TRC

Product number: R701015
Product name: RS39604Hydrochloride
Packaging: 50mg
Price: $695
Updated: 2021/12/16

ApexBio Technology

Product number: B5042
Product name: RS39604hydrochloride
Packaging: 50mg
Price: $1127
Updated: 2021/12/16

ApexBio Technology

Product number: B5042
Product name: RS39604hydrochloride
Packaging: 10mg
Price: $266
Updated: 2021/12/16

More

Less

1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

RS 39604 Hydrochloride is a potent, selective and orally active 5-HT4 receptor antagonist.

Definition

ChEBI: RS 39604 hydrochloride is a hydrochloride salt obtained by mixing equimolar amounts of RS 39604 with hydrochloric acid. A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and alpha1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies. It has a role as a serotonergic antagonist. It contains a RS 39604(1+).

Biological Activity

A potent and selective 5-HT 4 antagonist, with a pK i of 9.1 at 5-HT 4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT 1A, 2C, 3 and D 1 , D 2 , M 1 , M 2 , AT 1, B 1 and α 1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.

storage

Store at RT

1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE Suppliers

China 6 Germany 1 United Kingdom 2 United States 6 Global 15

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2982
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 4297
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24648
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 4870
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19863
Advantage: 58

167710-87-4, 1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDERelated Search:

1-(4-Amino-2-hydroxy-phenyl)-propan-1-one 3-(BENZYLOXY)-4-METHYLPHENYLAMINE 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE 5-CHLORO-2-[(3-METHOXYBENZYL)OXY]BENZALDEHYDE 1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[(1-2-METHYLSULPHONYLAMINO)ETHYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE 1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE

RS 39604 HYDROCHLORIDE

1-[4-AMINO-5-CHLORO-2-(3,5-DIMETHOXYPHENYL)METHYLOXY]-3-[[1-[2-METHYLSULPHONYLAMINO]ETHYL]PIPERIDIN-4-YL]PROPAN-1-ONE HYDROCHLORIDE

1-(4-Amino-5-chloro-2-(3,5-dimethoxyphenyl)methyloxy)-3-(1-(2-methylsulfonylamino)ethyl)piperidin-4-yl)propan-1-onehyd

RS39604HCl

1-(4-Amino-5-Chloro-2-(3,5-Dimethoxyphenyl)Methyloxy)-3-(1-(2-Methylsulfonylamino)Ethyl)Piperidin-4-

1-[4-Amino-5-Chloro-2-(3,5-Dimethoxyphenyl)Methyloxy]-3-[[1-[2-Methylsulphonylamino]Ethyl]Piperidin-4-Yl]Propan-1-One Hydrochloride

RS 39604

167710-87-4

C26H37Cl2N3O6S

C26H36ClN3O6SHCl