ChemicalBook > CAS DataBase List > 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride

1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride

Product Name
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride
CAS No.
1164469-60-6
Chemical Name
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride
Synonyms
KT-611 hydrochloride;Emorfazone Impurity 3;BM-15275 hydrochloride;Naftopidil hydrochloride, 10 mM in DMSO;1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride;BM-15275,BM15275,canine,prostatic,Naftopidil,prostate,hyperplasia,inhibit,Inhibitor,Naftopidil hydrochloride,KT-611,Adrenergic Receptor,KT611,KT 611,pressure,BM 15275,Beta Receptor
CBNumber
CB73845715
Molecular Formula
C24H29ClN2O3
Formula Weight
428.95166
MOL File
1164469-60-6.mol
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride Property

storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL; DMSO: 3 mg/mL
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21122
Product name
Naftopidil (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
21122
Product name
Naftopidil (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
21122
Product name
Naftopidil (hydrochloride)
Purity
≥98%
Packaging
100mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
21122
Product name
Naftopidil (hydrochloride)
Purity
≥98%
Packaging
250mg
Price
$380
Updated
2024/03/01
TRC
Product number
N213508
Product name
Naftopidil hydrochloride
Packaging
5mg
Price
$140
Updated
2021/12/16
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride Chemical Properties,Usage,Production

Uses

Naftopidil Hydrochloride is an α-1-adrenergic receptor antagonist. Naftopidil is used as an antihypertensive.

in vivo

Naftopidil hydrochloride (10 mg/kg; p.o; daily; for 28 days) decreases microvessel density (MVD) in E9+PrSC tumors mice model[2].

Animal Model:Male athymic mice(7-8 weeks), with E9+PrSC xenograft[2]
Dosage:10 mg/kg
Administration:Oral administration, daily, for 28 days
Result:Decreased tumor weights.

IC 50

Alpha-1A adrenergic receptor: 3.7 nM (Ki); Alpha-1B adrenergic receptor: 20 nM (Ki); Alpha-1D adrenergic receptor: 1.2 nM (Ki)

storage

Store at RT

1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride Suppliers

China 23 United Kingdom 1 United States 5 Global 29
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
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3008007409@qq.com
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
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China
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Chengdu Saint - Kay Biotechnology Co., Ltd.
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028-85157043 15882256948
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676046971@qq.com
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China
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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774
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sales@glpbio.cn
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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cindy.huang@synzest.com
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China
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1164469-60-6, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochlorideRelated Search:


  • 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol:hydrochloride
  • BM-15275 hydrochloride
  • KT-611 hydrochloride
  • BM-15275,BM15275,canine,prostatic,Naftopidil,prostate,hyperplasia,inhibit,Inhibitor,Naftopidil hydrochloride,KT-611,Adrenergic Receptor,KT611,KT 611,pressure,BM 15275,Beta Receptor
  • Emorfazone Impurity 3
  • Naftopidil hydrochloride, 10 mM in DMSO
  • 1164469-60-6