(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)
- Product Name
- (S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)
- CAS No.
- 385800-16-8
- Chemical Name
- (S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)
- Synonyms
- MX 1094;LT-NS 001;Naproxen etemesil;Zotepine Impurity3;(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate;(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261);2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, 2-(methylsulfonyl)ethyl ester, (αS)-
- CBNumber
- CB73909381
- Molecular Formula
- C17H20O5S
- Formula Weight
- 336.4027
- MOL File
- 385800-16-8.mol
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261) Property
- Boiling point:
- 542.0±35.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261) Chemical Properties,Usage,Production
Uses
Naproxen Etemesil, is a lipophilic, non-acidic, inactive prodrug of naproxen, that is a well known nonsteroidal anti-inflammatory drug.
in vivo
Naproxen exerts an anti-inflammatory and antifibrotic effect in mouse model of bleomycin-induced lung fibrosis. Naproxen also downregulates TGF-β levels and Smad3/4 complex formation[2]. Naproxen is shown to inhibit the time-courses of pain, fever and PGE2 with similar potencies (IC50=27, 40, 13 μM)[3].
(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261) Preparation Products And Raw materials
Raw materials
Preparation Products
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