ChemicalBook > CAS DataBase List > AZD4573

AZD4573

Product Name: AZD4573
CAS No.: 2057509-72-3
Chemical Name: AZD4573
Synonyms: (1S,3R)-3-acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexane-1-carboxamide;AZD4573;AZD4573 AZD-4573;AZD4573, 10 mM in DMSO;AZD-4573;AZD4573;AZD 4573;AZD 4573,inhibit,CDK,AZD4573,AZD-4573,Inhibitor,Cyclin dependent kinase;(1S,3R)-N-(5-chloro-4-{5,5-dimethyl-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl}pyridin-2-yl)-3-acetamidocyclohexane-1-carboxamide;(1S,3R)-3-Acetamido-N-[5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-pyridyl]cyclohexanecarboxamide;(1S,3R)-3-acetamido-N-[5-chloro-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide;(1S,3R)-3-Acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexanecarboxamide
CBNumber: CB73954558
Molecular Formula: C22H28ClN5O2
Formula Weight: 429.94
MOL File: 2057509-72-3.mol

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AZD4573 Property

Boiling point:: 692.8±55.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 125 mg/mL (290.74 mM)
form: Solid
pka: 12.28±0.40(Predicted)
color: White to off-white
InChIKey: AVIWDYSJSPOOAR-LSDHHAIUSA-N
SMILES: [C@H]1(C(NC2=NC=C(Cl)C(C3C=NN4CC(C)(C)CC4=3)=C2)=O)CCC[C@@H](NC(C)=O)C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A808275
Product name: AZD4573
Packaging: 2.5mg
Price: $210
Updated: 2021/12/16

TRC

Product number: A808275
Product name: AZD4573
Packaging: 25mg
Price: $1680
Updated: 2021/12/16

ChemScene

Product number: CS-0043316
Product name: AZD4573
Purity: 99.90%
Packaging: 5mg
Price: $380
Updated: 2021/12/16

ChemScene

Product number: CS-0043316
Product name: AZD4573
Purity: 99.90%
Packaging: 10mg
Price: $590
Updated: 2021/12/16

ChemScene

Product number: CS-0043316
Product name: AZD4573
Purity: 99.90%
Packaging: 25mg
Price: $1180
Updated: 2021/12/16

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AZD4573 Chemical Properties,Usage,Production

Uses

AZD4573, is a CDK9 inhibitor.

in vivo

AZD4573 exhibits a short half-life in multiple species (less than one hour in rat, dog and monkey) and good solubility for intravenous administration^[1].

IC 50

CDK9: 4 nM (IC₅₀)

AZD4573 Preparation Products And Raw materials

Raw materials

Preparation Products

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2057509-72-3, AZD4573Related Search:

AZD4573

(1S,3R)-3-acetamido-N-[5-chloro-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide

AZD-4573;AZD4573;AZD 4573

(1S,3R)-N-(5-chloro-4-{5,5-dimethyl-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl}pyridin-2-yl)-3-acetamidocyclohexane-1-carboxamide

Cyclohexanecarboxamide, 3-(acetylamino)-N-[5-chloro-4-(5,6-dihydro-5,5-dimethyl-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-pyridinyl]-, (1S,3R)-

(1S,3R)-3-acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexane-1-carboxamide

AZD 4573,inhibit,CDK,AZD4573,AZD-4573,Inhibitor,Cyclin dependent kinase

(1S,3R)-3-Acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexanecarboxamide

AZD4573 AZD-4573

(1S,3R)-3-Acetamido-N-[5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-pyridyl]cyclohexanecarboxamide

AZD4573, 10 mM in DMSO

2057509-72-3

C22H28ClN5O2