4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

Product Name: 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
CAS No.: 1452128-53-8
Chemical Name: 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Synonyms: Afanafine;Avanafil-005;Avana non impurity;Avanafil Keto Analog;4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide;5-Pyrimidinecarboxamide, 6-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1,2-dihydro-2-oxo-N-(2-pyrimidinylmethyl)-
CBNumber: CB73959104
Molecular Formula: C18H17ClN6O3
Formula Weight: 400.82
MOL File: 1452128-53-8.mol

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4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Property

Density: 1.46±0.1 g/cm3(Predicted)
pka: 7.79±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Chemical Properties,Usage,Production

Uses

4-((3-Chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide is an impurity of Avanafil (A794670). Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Suppliers

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1452128-53-8, 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamideRelated Search:

Avanafil impurity 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylsulfinylpyriMidine Avanafil 5-Pyrimidinecarboxamide, 2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-4-[[(4-methoxyphenyl)methyl]amino]-N-(2-pyrimidinylmethyl)- Avanafil iMpurity 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Avanafil Impurity

Avanafil-005

Avanafil Keto Analog

Avana non impurity

5-Pyrimidinecarboxamide, 6-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1,2-dihydro-2-oxo-N-(2-pyrimidinylmethyl)-

4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide

Afanafine

1452128-53-8