N-NITROSODI-N-PROPYLAMINE Property

Boiling point:

113 °C / 40mmHg

Density 

0.92

refractive index 

1.4468 (589.3 nm 20℃)

Flash point:

10 °C

storage temp. 

Inert atmosphere,2-8°C

solubility 

Very soluble in ethanol and ether (quoted, Keith and Walters, 1992)

pka

-3.18±0.70(Predicted)

color 

Yellow to gold colored liquid

Water Solubility 

9,900 mg/L at 25 °C (Mirvish et al., 1976)

IARC

2B (Vol. 17, Sup 7) 1987

EPA Substance Registry System

N-Nitrosodi-n-propylamine (621-64-7)

Safety

Hazard Codes 

T,N,F

Risk Statements 

45-22-51/53-39/23/24/25-23/24/25-11

Safety Statements 

53-45-61-36/37-16

RIDADR 

2810

WGK Germany 

3

RTECS 

JL9700000

HS Code 

2921.29.0055

HazardClass 

6.1(b)

PackingGroup 

III

Hazardous Substances Data

621-64-7(Hazardous Substances Data)

Toxicity

Acute oral LD50 for rats 480 mg/kg (quoted, RTECS, 1985).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

N-NITROSODI-N-PROPYLAMINE Chemical Properties,Usage,Production

Chemical Properties

Yellow Oil

Chemical Properties

N-nitrosodi-N-propylamine is a yellow liquid.

Uses

N-Nitrosodi-n-propylamine is used in small quantities in laboratory research. It has no known commercial use (IARC 1978, ATSDR 1989, HSDB 2009).

Uses

Research chemical; impurity in herbicides treflan, isopropalin, and trifluralin; contaminant in wastewater from chemical factories and production of cheese and brandy and other liquors. N-nitrosamines are frequently produced during rubber processing and may be airborne in the workplace.

Definition

ChEBI: N-Nitrosodi-n-propylamine is a nitroso compound.

General Description

Clear to pale yellow liquid.

Reactivity Profile

N-NITROSODI-N-PROPYLAMINE is a nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic.

Fire Hazard

Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

Potential Exposure

N-nitrosodi-N-propylamine is used in the manufacture of plastics, resins, rubber, and synthetic textiles. There is no evidence that N-nitrosodi-N-propylamine exists naturally in soil, air, food, or water. Small quantities of N-nitrosodi-N-propylamine are inadvertently produced during some manufacturing processes; as an impurity in some commercially available dinitroaniline based weed killers, and during the manufacture of some rubber products. However, according to Sax, some similar N-nitroso compounds are formed in the environment and absorbed from precursors in food, water, or air; from tobacco; and from naturally occurring compounds.

Carcinogenicity

N-Nitrosodi-n-propylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Environmental Fate

Chemical/Physical. N-Nitroso-n-propylamine will not hydrolyze because it does not contain a hydrolyzable functional group (Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities were 24, 13, 7.4, and 4.0 mg/g, respectively (Dobbs and Cohen, 1980).

Shipping

UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Sensitive to UV light.

Waste Disposal

N-Nitrosodi-N-propylamine may be destroyed by high temperature incineration in an incinerator equipped with an nitrogen oxide scrubber. Chemical treatment methods may also be used to destroy N-nitrosodi-N-propylamine. These methods involve (a) denitrosation by reaction with 3% hydrobromic acid in glacial acetic acid; (b) oxidation by reaction with potassium permanganate-sulfuric acid; or (c) extraction of the nitrosamine from the waste using dichloromethane and subsequent reaction with triethyloxonium tetrafluoroborate (TOEF). Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.