1,8-Diamino-3,6-dioxaoctane
- Product Name
- 1,8-Diamino-3,6-dioxaoctane
- CAS No.
- 929-59-9
- Chemical Name
- 1,8-Diamino-3,6-dioxaoctane
- Synonyms
- 1,2-BIS(2-AMINOETHOXY)ETHANE;2,2'-(ethane-1,2-diylbis(oxy))diethanamine;NH2-PEG2-NH2;2,2'-(Ethane-1,2-diylbis(oxy))bis(ethan-1-amine);EDR-148;Amino-PEG2-Amine;2-[2-(2-aminoethoxy)ethoxy]ethanamine;1,2-Bis(2-aMinoethoxy)ethane, 98%, 98%;DA -10;NSC 28972
- CBNumber
- CB7408955
- Molecular Formula
- C6H16N2O2
- Formula Weight
- 148.2
- MOL File
- 929-59-9.mol
1,8-Diamino-3,6-dioxaoctane Property
- Boiling point:
- 105-109 °C6 mm Hg(lit.)
- Density
- 1.015 g/mL at 25 °C(lit.)
- vapor pressure
- 71Pa at 20℃
- refractive index
- n20/D 1.461(lit.)
- Flash point:
- >230 °F
- storage temp.
- Store below +30°C.
- solubility
- soluble in Dimethylformamide, Methanol
- form
- Liquid
- pka
- 9.04±0.10(Predicted)
- color
- Colorless to Almost colorless
- Water Solubility
- Soluble in 0.4 parts water.
- Sensitive
- Hygroscopic
- BRN
- 1739187
- Cosmetics Ingredients Functions
- NOT REPORTED
- InChI
- 1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2
- InChIKey
- IWBOPFCKHIJFMS-UHFFFAOYSA-N
- SMILES
- NCCOCCOCCN
- CAS DataBase Reference
- 929-59-9(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanamine, 2,2'-[1,2-ethanediylbis(oxy)]bis- (929-59-9)
Safety
- Hazard Codes
- C
- Risk Statements
- 22-34-42/43-37
- Safety Statements
- 23-26-36/37/39-45
- RIDADR
- UN 2735 8/PG 2
- WGK Germany
- 3
- F
- 34
- TSCA
- TSCA listed
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29221990
- Storage Class
- 8A - Combustible corrosive hazardous materials
- Hazard Classifications
- Acute Tox. 4 Oral
Eye Dam. 1
Resp. Sens. 1
Skin Corr. 1B
Skin Sens. 1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.18116
- Product name
- 1,8-Diamino-3,6-dioxaoctane
- Purity
- for synthesis
- Packaging
- 25mL
- Price
- $32.5
- Updated
- 2025/07/31
- Product number
- 8.18116
- Product name
- 1,8-Diamino-3,6-dioxaoctane
- Purity
- for synthesis
- Packaging
- 100mL
- Price
- $77.8
- Updated
- 2025/07/31
- Product number
- 385506
- Product name
- 2,2′-(Ethylenedioxy)bis(ethylamine)
- Purity
- 98%
- Packaging
- 100ml
- Price
- $81.1
- Updated
- 2025/07/31
- Product number
- 385506
- Product name
- 2,2′-(Ethylenedioxy)bis(ethylamine)
- Purity
- 98%
- Packaging
- 5l
- Price
- $1530
- Updated
- 2025/07/31
- Product number
- B1431
- Product name
- 1,2-Bis(2-aminoethoxy)ethane
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $37
- Updated
- 2025/07/31
1,8-Diamino-3,6-dioxaoctane Chemical Properties,Usage,Production
Description
Amino-PEG2-Amine is a crosslinker containing two amino groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
2,2'-(Ethylenedioxy)bis(ethylamine) is used to linker to form conjugates of manganese-doped zinc sulfide nanoparticles with folic acid.
Application
1,8-Diamino-3,6-dioxaoctane is a chelating agent that has been shown to have antibacterial efficacy against gram-positive bacteria. It has been demonstrated to bind to a variety of functionalities such as amines, low energy metals, and hydroxy groups. It has been studied in the synthesis of coordination complexes with a range of geometric structures. The synthesis methods for this compound include solid-phase synthesis and hydrolysis of ethylenediamine. This compound has also been used as an electron donor in fluorescence techniques and morphology studies.
Definition
ChEBI: Ethylene glycol bis(2-aminoethyl) ether is an ether.
Flammability and Explosibility
Not classified
Synthesis
Step 1, Synthesis of 1,6-dicyano-2,5-dioxohexane
Sodium hydride (88 g, 2.2 mol) and tetrahydrofuran were added to a 5L three-necked flask, and cooled to 0 C in an ice bath. A tetrahydrofuran solution of ethylene glycol (62.07 g, 1 mol) was added dropwise. Then the reaction was naturally raised to room temperature for 4h, then the ice bath was cooled down to 0C and a tetrahydrofuran solution of bromoacetonitrile (239.9g, 2.0 mol) was added dropwise to the reaction solution, which was naturally raised to room temperature after dropping, and the reaction was continued for 18h (overnight), and the reaction was stopped when mono-substituted impurities were monitored to be almost consumed by TLC. The reaction solution was cooled down and quenched with methanol, and a small amount of silica gel and diatomaceous earth was spread in a Brinell's funnel to filter the reaction solution, which was concentrated to obtain 113.5 g of 111,6-dicyano-2,5-dioxahexane in 81% yield.
Step 2, Synthesis of 1,8-diamino-3,6-dioxaoctane
1,6-dicyano-2,5-dioxohexane (100 g, 0.71 mol), 1 L of methanol, and Pd/C (25 g, 25%) were placed in a 2 L three-neck flask. Then hydrogen was passed into the reaction solution until the end of the reaction, and then the hydrogen was stopped. After filtration and concentration, crude 1,8-diamino-3,6-dioxaoctane was obtained, and 79.3 g of pure 1,8-diamino-3,6-dioxaoctane was obtained after distillation under reduced pressure in 75% yield.1,8-Diamino-3,6-dioxaoctane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,8-Diamino-3,6-dioxaoctane manufacturers
- Product
- 1,8-Diamino-3,6-dioxaoctane 929-59-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 20kg
- Purity
- 98%min
- Supply Ability
- 100 tons
- Release date
- 2025-12-22
- Product
- 2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-amine) 929-59-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-10
- Product
- Amino-PEG2-amine 929-59-9
- Price
- US $325.00/Kg
- Min. Order
- 0.100Kg
- Purity
- 98
- Supply Ability
- 5000 Kg
- Release date
- 2025-03-06