ChemicalBook > CAS DataBase List > 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE

2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE

Product Name
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
CAS No.
137830-77-4
Chemical Name
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
Synonyms
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE;2H-1,2,6-Thiadiazine, tetrahydro-2-methyl-, 1,1-dioxide;2-methyl-3,4,5,6-tetrahydro-1,2,6-thiadiazine-1,1-dioxide
CBNumber
CB7438833
Molecular Formula
C4H10N2O2S
Formula Weight
150.2
MOL File
137830-77-4.mol
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2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Property

Boiling point:
241.6±23.0 °C(Predicted)
Density 
1.250±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.50±0.20(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M335083
Product name
2-Methyl-1,2,6-thiadiazinane1,1-dioxide
Packaging
10mg
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-W006251
Product name
2-Methyl-1,2,6-thiadiazinane1,1-dioxide
Packaging
100mg
Price
$69
Updated
2021/12/16
ChemScene
Product number
CS-W006251
Product name
2-Methyl-1,2,6-thiadiazinane1,1-dioxide
Packaging
250mg
Price
$115
Updated
2021/12/16
ChemScene
Product number
CS-W006251
Product name
2-Methyl-1,2,6-thiadiazinane1,1-dioxide
Packaging
1g
Price
$290
Updated
2021/12/16
Matrix Scientific
Product number
093279
Product name
2-Methyl-1,2,6-thiadiazinane 1,1-dioxide
Purity
95+%
Packaging
250mg
Price
$325
Updated
2021/12/16
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2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Chemical Properties,Usage,Production

Synthesis

6291-84-5

137830-77-4

The general procedure for the synthesis of 2-methyl-[1,2,6]thiadiazine 1,1-dioxide from 3-methylaminopropylamine was as follows: a mixture of N-methyl-1,3-propanediamine (2.06 g, 23.4 mmol) and sulfonamide (0.748 g, 7.78 mmol) was placed in a microwaveable reaction flask, sealed, and then filled with argon gas for protection. The reaction flask was stirred overnight at 50°C, and then warmed to 160°C to continue the reaction with stirring for 20 minutes. Upon completion of the reaction, the reaction mixture was concentrated and the residue was purified by column chromatography to afford 2-methyl-1,2,6-thiadiazine 1,1-dioxide (0.82 g, 70% yield).

References

[1] Journal of Medicinal Chemistry, 1994, vol. 37, # 19, p. 3023 - 3032
[2] European Journal of Medicinal Chemistry, 2007, vol. 42, # 9, p. 1176 - 1183
[3] Patent: WO2015/108861, 2015, A1. Location in patent: Paragraph 00401
[4] Patent: US2015/225422, 2015, A1. Location in patent: Paragraph 0555-0556
[5] Patent: US2013/303524, 2013, A1. Location in patent: Paragraph 0405-0406

2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Suppliers

China 42 India 2 United Kingdom 1 United States 7 Global 52
Fulcrum Scientific Ltd.
Tel
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Country
United Kingdom
ProdList
6565
Advantage
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137830-77-4, 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDERelated Search:

4-[(1,1-Dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE 2-Benzyl-1,2,6-thiadiazinane-1,1-dione

  • 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
  • 2-methyl-3,4,5,6-tetrahydro-1,2,6-thiadiazine-1,1-dioxide
  • 2H-1,2,6-Thiadiazine, tetrahydro-2-methyl-, 1,1-dioxide
  • 137830-77-4