2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
- Product Name
- 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
- CAS No.
- 137830-77-4
- Chemical Name
- 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE
- Synonyms
- 2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE;2H-1,2,6-Thiadiazine, tetrahydro-2-methyl-, 1,1-dioxide;2-methyl-3,4,5,6-tetrahydro-1,2,6-thiadiazine-1,1-dioxide
- CBNumber
- CB7438833
- Molecular Formula
- C4H10N2O2S
- Formula Weight
- 150.2
- MOL File
- 137830-77-4.mol
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Property
- Boiling point:
- 241.6±23.0 °C(Predicted)
- Density
- 1.250±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 12.50±0.20(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M335083
- Product name
- 2-Methyl-1,2,6-thiadiazinane1,1-dioxide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W006251
- Product name
- 2-Methyl-1,2,6-thiadiazinane1,1-dioxide
- Packaging
- 100mg
- Price
- $69
- Updated
- 2021/12/16
- Product number
- CS-W006251
- Product name
- 2-Methyl-1,2,6-thiadiazinane1,1-dioxide
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- CS-W006251
- Product name
- 2-Methyl-1,2,6-thiadiazinane1,1-dioxide
- Packaging
- 1g
- Price
- $290
- Updated
- 2021/12/16
- Product number
- 093279
- Product name
- 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $325
- Updated
- 2021/12/16
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Chemical Properties,Usage,Production
Synthesis
6291-84-5
137830-77-4
The general procedure for the synthesis of 2-methyl-[1,2,6]thiadiazine 1,1-dioxide from 3-methylaminopropylamine was as follows: a mixture of N-methyl-1,3-propanediamine (2.06 g, 23.4 mmol) and sulfonamide (0.748 g, 7.78 mmol) was placed in a microwaveable reaction flask, sealed, and then filled with argon gas for protection. The reaction flask was stirred overnight at 50°C, and then warmed to 160°C to continue the reaction with stirring for 20 minutes. Upon completion of the reaction, the reaction mixture was concentrated and the residue was purified by column chromatography to afford 2-methyl-1,2,6-thiadiazine 1,1-dioxide (0.82 g, 70% yield).
References
[1] Journal of Medicinal Chemistry, 1994, vol. 37, # 19, p. 3023 - 3032
[2] European Journal of Medicinal Chemistry, 2007, vol. 42, # 9, p. 1176 - 1183
[3] Patent: WO2015/108861, 2015, A1. Location in patent: Paragraph 00401
[4] Patent: US2015/225422, 2015, A1. Location in patent: Paragraph 0555-0556
[5] Patent: US2013/303524, 2013, A1. Location in patent: Paragraph 0405-0406
2-METHYL-[1,2,6]THIADIAZINANE 1,1-DIOXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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