HEPTAMETHYLDISILAZANE Property

Boiling point:

144-147 °C(lit.)

Density 

0.799 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.421(lit.)

solubility 

sol ether, alcohol, dichloromethane, and most organic solvents; hydrochloride salt sol in H2O, alcohol, DMF, DMSO.

form 

clear liquid

pka

11.57±0.29(Predicted)

color 

Colorless to Almost colorless

Safety

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

F 

10

HS Code 

2931.90.9010

HazardClass 

8/3

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

HEPTAMETHYLDISILAZANE Chemical Properties,Usage,Production

Physical properties

colorless liquid, bp 70°Cat 25 mm Hg; its hydrochloride salt, mp 191 °C.

Uses

Methanamine, 1,1-Bis(trimethylsilyl) is reagent used for the preparation of N-bis(trimethylsilyl)methyl amines, imines, as a synthetic equivalent of N-methyl, N- (trimethylsilyl)methyl carbanion, and [N-CH] dianion synthons, as an N-protecting group.

Preparation

It is prepared by lithium metal mediated reductive silylation of trimethylsilyl cyanide.