ChemicalBook > CAS DataBase List > 5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide

5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide

Product Name
5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
CAS No.
874146-69-7
Chemical Name
5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
Synonyms
PK11007, 10 mM in DMSO;PK11007;PK-11007;PK 11007;PK11007,inhibit,MDM-2/p53,Reactive Oxygen Species,Inhibitor,PK 11007,PK-11007;5-Chloro-2-((4-fluorobenzyl)sulfonyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide;5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide;5-Chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide;4-Pyrimidinecarboxamide,5-chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-
CBNumber
CB74461707
Molecular Formula
C15H11ClFN5O3S2
Formula Weight
427.86
MOL File
874146-69-7.mol
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5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide Property

Density 
1.610±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
4.18±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0106640
Product name
PK11007
Purity
99.0%
Packaging
5mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0106640
Product name
PK11007
Purity
99.0%
Packaging
10mg
Price
$190
Updated
2021/12/16
ChemScene
Product number
CS-0106640
Product name
PK11007
Purity
99.0%
Packaging
25mg
Price
$370
Updated
2021/12/16
ChemScene
Product number
CS-0106640
Product name
PK11007
Purity
99.0%
Packaging
50mg
Price
$560
Updated
2021/12/16
ChemScene
Product number
CS-0106640
Product name
PK11007
Purity
99.0%
Packaging
100mg
Price
$850
Updated
2021/12/16
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5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide Chemical Properties,Usage,Production

Uses

5-Chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide is used as a mild alkylating agents with anticancer activity toward p53-compromised cells.

5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide Suppliers

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874146-69-7, 5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamideRelated Search:


  • 5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
  • PK11007;PK-11007;PK 11007
  • 5-Chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide
  • 4-Pyrimidinecarboxamide,5-chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-
  • 5-Chloro-2-((4-fluorobenzyl)sulfonyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
  • PK11007,inhibit,MDM-2/p53,Reactive Oxygen Species,Inhibitor,PK 11007,PK-11007
  • PK11007, 10 mM in DMSO
  • 874146-69-7