FERROUS SULFATE Property

Melting point:

decomposes at 671℃ [JAN85]

Density 

3.650

vapor pressure 

0Pa at 20℃

storage temp. 

Store at +15°C to +25°C.

solubility 

Water (Slightly)

form 

white orthorhombic crystals

color 

white orthorhombic crystals, crystalline; hygroscopic

Odor

at 100.00?%. odorless

Water Solubility 

g/100g solution H2O: 13.6 (0°C), 22.8 (25°C), 24.0 (100°C); solid phase, FeSO4 · 7H2O (0°C, 25°C), FeSO4 ·H2O (100°C) [KRU93]

Dielectric constant

14.2（14℃）

InChI

InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChIKey

BAUYGSIQEAFULO-UHFFFAOYSA-L

SMILES

[Fe+2].S([O-])([O-])(=O)=O

CAS DataBase Reference

7720-78-7(CAS DataBase Reference)

NIST Chemistry Reference

Ferrous sulfate(7720-78-7)

EPA Substance Registry System

Ferrous sulfate (7720-78-7)

Safety

Risk Statements 

25

Safety Statements 

45

HS Code 

28332910

Hazardous Substances Data

7720-78-7(Hazardous Substances Data)

Toxicity

LD50 oral in rat: 319mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

FERROUS SULFATE Chemical Properties,Usage,Production

Uses

• Nutritional supplements (iron enhancer); color former of fruit and vegetable; for example, the salted product used together with dried alum in eggplant can form stable complex salt with its pigment to prevent the discoloration caused by organic acids. However, it should be noted, for example, it will turn into black ink upon excess amount of iron. When the amount of alum is high, the meat of the pickled eggplant meat will become excessively solid. Formulation example: long eggplant 300 kg; edible salt 40kg; ferrous sulfate 100g; dried alum 500g. It can still be used as the color forming agent of black beans, sugar boiled beans and kelp. Food containing tannins, in order to avoid of causing blackening, should not be used. It can also be used for sterilization, deodorization and very weakly bactericidal.
• Legumes contained cryptochromic pigment is colorless upon reduction state while being oxidized into black upon oxidation in alkaline condition. Taking advantage of the reduction property of ferrous sulfate can achieve the purpose of color protection with the usage amount of 0.02% to 0.03%.
• If is used for the manufacturing of iron salt, iron oxide pigments, mordant, purifying agent, preservatives, disinfectants and medicine for anti-anemia drugs

Toxicity

LD50: 279 to 558 mg/kg (rat, oral, calculated as Fe).
GRAS (FDA, § 182.5315, §184.1315, 2000);
ADI 0.8 mg Fe/kg (calculated in terms of Fe; FAO/WHO, 2001);

Hazards & Safety Information

Category :Toxic substances
Toxicity classification: highly toxic
Acute Toxicity : Oral-Rat LD50 319 mg/kg; Oral-mouse LD50: 680 mg/kg
Flammability and Hazardous characteristics: Non-combustible with fire producing toxic iron-containing fumes
Storage and transportation characteristics  Treasury: low temperature, ventilated, dry; store separately from food raw materials.
Fire extinguishing agent : water, carbon dioxide, dry powder, sand
Occupational Standard  :TWA 1 mg (iron)/m3

Description

Green vitriol, FeSO4.7H20, has been known since the thirteenth century ; it crystallizes from solutions of iron or iron bases in dilute sulphuric acid. The heptahydrate forms green monoclinic crystals of density 1·88, very soluble in water (296 g litre^-1 FeS04 at 25°C). By precipitating the aqueous solution with ethanol, heating the heptahydrate to 140° in vacuo or by crystallizing it from 50 % sulphuric acid, the white monohydrate is obtained. This can be further dehydrated to the white, amorphous FeSO4 by heating to 300° in a current of hydrogen. At red heat the sulphate decomposes : 2FeS04 -> Fe203+S02+S03 A tetrahydrate, FeS04.4H20, crystallizes from aqueous solutions above 56°.

Chemical Properties

Greenish or yellow-brown crystals or granules; odorless. Soluble in water with saline taste; insoluble in alcohol. hygroscopic.

Chemical Properties

Ferrous sulfate is a greenish or yellowish solid in fine or lumpy crystals.

Physical properties

White orthorhombic crystal; hygroscopic; density 3.65 g/cm³; soluble in water (26.6g/100g water at 20°C). The monohydrate is a yellowish-white monoclinic crystal; density 3.0 g/cm³; decomposes at 300°C; soluble in water. Heptahydrate is bluish-green monoclinic crystal; refractive index 1.47; hardness 2 Mohs; density 1.89g/cm上3; decomposes at about 60°C; very soluble in water; soluble in absolute methanol; slightly soluble in ethanol.

Occurrence

Iron(II) sulfate is probably the most important salt of iron, as well as the longest-known iron(II) compound. The compound is used as a mordant in dyeing; as a component of writing ink; in electroplating baths; in radiation dosimeters; in lithography and engraving; as a weed-killer; and in water purification. A major application of this compound is in the manufacture of other iron(II) salts including Prussian blue or ferric ferrocyanide. Iron(II) sulfate also is used as a reducing agent and an analytical reagent (in brown ring test for nitrate).

Uses

Ferrous sulfate (FeSO4) is also known as iron sulfate or iron vitriol. It is used in the production of various chemicals, such as sulfur dioxide and sulfuric acid.

Uses

Ferrous Sulfate is a nutrient and dietary supplement that is a source of iron. it is a white to grayish odorless powder. ferrous sulfate hep- tahydrate contains approximately 20% iron, while ferrous sulfate dried contains approximately 32% iron. it dissolves slowly in water and has high bioavailability. it can cause discoloration and rancidity. it is used for fortification of baking mixes. in the encapsulated form it does not react with lipids in cereal flours. it is used in infant foods, cereals, and pasta products.

Uses

Iron Supplement

Production Methods

Iron(II) sulfate in industrial scale is mostly produced in the pickling process as a by-product of the steel industry. It is obtained when the surface of steel is cleaned with dilute sulfuric acid to remove metal impurities. In the laboratory iron(II) sulfate heptahydrate may be prepared by dissolving iron in dilute sulfuric acid in a reducing atmosphere, followed by crystallization:
Fe + H₂SO₄ → FeSO₄ + H₂
Alcohol may be added to the aqueous solution to speed up crystallization; iron(II) may otherwise oxidize to iron(III) during a slow crystallization process.
Iron(II) oxide or carbonate may be used instead of iron metal to prepare the heptahydrate.
.

Definition

A rusty-brown solid prepared by the action of heat on iron(III) hydroxide or iron(II) sulfate. It occurs in nature as the mineral hematite. Industrially it is obtained by roasting iron pyrites. Iron(III) oxide dissolves in dilute acids to produce solutions of iron(III) salts. It is stable at red heat, decomposes around 1300°C to give triiron tetroxide, and can be reduced to iron by hydrogen at 1000°C. Iron(III) oxide is not ionic in character but has a structure similar to that of aluminum(III) oxide.

Definition

Copperas: an off-whitesolid, FeSO₄.H₂O; monoclinic; r.d.2.970. There is also a heptahydrate,FeSO₄.7H₂O; blue-green monoclinic;r.d. 1.898; m.p. 64°C. The heptahydrateis the best known iron(II) saltand is sometimes called green vitriolor copperas. It is obtained by the actionof dilute sulphuric acid on ironin a reducing atmosphere. The anhydrouscompound is very hygroscopic.It decomposes at red heat to giveiron(III) oxide, sulphur trioxide, andsulphur dioxide. A solution of iron(II)sulphate is gradually oxidized on exposureto air, a basic iron(III) sulphatebeing deposited.

Hazard

Ingestion causes intestinal disorders.

Flammability and Explosibility

Non flammable

Agricultural Uses

Copperas, also called green vitriol, is ferrous sulphate heptahydrate. It is an iron salt fertilizer, which is most effective in overcoming iron deficiency.

Agricultural Uses

Ferrous sulphate heptahydrate (FeSO₄.7H₂O), also called green vitriol or copperas, is a blue-green water-soluble crystal and is the best known ferrous salt. It is obtained by the action of dilute sulphuric acid on iron in a reducing atmosphere. The anhydrous compound is very hygroscopic. It gets oxidized gradually in an aqueous solution. On heating, the solid decomposes to give red ferric oxide, sulphur trioxide (SO₃) and sulphur dioxide (SO₂).

Clinical Use

Iron deficiency anaemia

Safety Profile

A human poison by ingestion. Moderately toxic to humans by an unspecified route. An experimental poison by ingestion, intraduodenal, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: aggression, somnolence, brain recorlng changes, diarrhea, nausea or vomiting, bleedmg from the stomach, coma. Questionable carcinogen with experimental tumorigenic data. Experimental teratogenic and reproductive effects. Mutation data reported. Potentially explosive reaction with methyl isocyanoacetate at 25'. May igmte on contact with arsenic trioxide + sodium nitrate. When heated to decomposition it emits toxic fumes of SOx. See also IRON COMPOUNDS.

Potential Exposure

It is used as a fertilizer, food or feed additive; and in herbicides; process engraving; dyeing, and water treatment. A byproduct of various chemical and metal treating operations.

Veterinary Drugs and Treatments

While iron is a necessary trace element in all hemoglobin-utilizing animals, the use of therapeutic dosages of ferrous sulfate (or other oral iron) preparations in veterinary medicine is limited primarily to the treatment of iron-deficiency anemias in dogs (usually due to chronic blood loss), and as adjunctive therapy in cats when receiving epoetin (erythropoietin) therapy. Injectable iron products are usually used in the treatment of iron deficiency anemias associated with newborn animals.

Drug interactions

Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption of mycophenolate.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note to physician: Gastric lavage with large amounts of 5%sodium phosphate or water. Follow this with a large amountof 1% sodium bicarbonate over a 3-h period.Note to physician: For severe poisoning do not use BAL[British Anti-Lewisite, dimercaprol, dithiopropanol(C3H8OS2)] as it is contraindicated or ineffective in poisoning from iron.

Metabolism

Following absorption, the majority of iron is bound to transferrin and transported to the bone marrow where it is incorporated into haemoglobin. The remainder is stored within ferritin or haemosiderin or is incorporated into myoglobin with smaller amounts occurring in haemcontaining enzymes or in plasma bound to transferrin.
Only very small amounts are excreted as the body reabsorbs the iron after the haemoglobin has broken down

storage

Color Code—Green: General storage may beused. Prior to working with this chemical you should betrained on its proper handling and storage. Store in tightlyclosed containers in a cool, well-ventilated area away fromalkalis.

Shipping

.

Incompatibilities

Aqueous solution is acidic. Contact with alkalies form iron. Keep away from alkalies, soluble carbo nates; gold and silver salts; lead acetate; lime water, potassium iodide; potassium and sodium tartrate; sodium borate; tannin.