(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE

Product Name: (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE
CAS No.: 745055-86-1
Chemical Name: (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE
Synonyms: UBP 296;(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE;1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-
CBNumber: CB7460159
Molecular Formula: C15H15N3O6
Formula Weight: 333.3
MOL File: Mol file

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(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Property

Melting point:: 190.8-191.2 °C (decomp)(Solv: water (7732-18-5))
Boiling point:: 603.0±65.0 °C(Predicted)
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: <3.33mg/ml in 1eq. NaOH; <3.33mg/ml in DMSO
pka: 2.12±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2078
Product name: UBP296
Purity: ≥98%(HPLC)
Packaging: 10
Price: $233
Updated: 2021/12/16

Tocris

Product number: 2078
Product name: UBP296
Purity: ≥98%(HPLC)
Packaging: 50
Price: $982
Updated: 2021/12/16

TRC

Product number: U103515
Product name: UBP296
Packaging: 10mg
Price: $215
Updated: 2021/12/16

Usbiological

Product number: 257005
Product name: UBP 296
Packaging: 10mg
Price: $495
Updated: 2021/12/16

TRC

Product number: U103515
Product name: UBP296
Packaging: 50mg
Price: $905
Updated: 2021/12/16

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(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Chemical Properties,Usage,Production

Uses

UBP 296 is a novel, potent and selective kainate receptor antagonist.

Definition

ChEBI: 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid is an alpha-amino acid.

Biological Activity

Selective and potent GluR5-subunit containing kainate receptor antagonist (apparent K D = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.

storage

Store at RT

(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Suppliers

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745055-86-1, (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONERelated Search:

(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE

UBP 296

1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-

745055-86-1

Glutamate receptor