SJ000291942
- Product Name
- SJ000291942
- CAS No.
- 425613-09-8
- Chemical Name
- SJ000291942
- Synonyms
- SJ000291942;SJ0000291942;SJ000291942 >=98% (HPLC);SJ000291942, 10 mM in DMSO;2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)acetamide;Acetamide, 2-(4-ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-;Transforming growth factor beta receptors,SJ 000291942,SJ000291942,SJ-000291942,TGF-β Receptor,inhibit,Inhibitor
- CBNumber
- CB74656565
- Molecular Formula
- C16H15FN2O4
- Formula Weight
- 318.3
- MOL File
- 425613-09-8.mol
SJ000291942 Property
- Boiling point:
- 525.4±50.0 °C(Predicted)
- Density
- 1.327±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml
- form
- A crystalline solid
- pka
- 11.44±0.70(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 29904
- Product name
- SJ000291942
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 29904
- Product name
- SJ000291942
- Packaging
- 25mg
- Price
- $388
- Updated
- 2024/03/01
- Product number
- 29904
- Product name
- SJ000291942
- Packaging
- 10mg
- Price
- $166
- Updated
- 2024/03/01
- Product number
- CS-0045238
- Product name
- SJ000291942
- Purity
- 99.20%
- Packaging
- 25mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- 0057CE
- Product name
- 2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)acetamide
- Packaging
- 10mg
- Price
- $282
- Updated
- 2021/12/16
SJ000291942 Chemical Properties,Usage,Production
Uses
2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)acetamide is a canonical bone morphogenetic proteins (BMP) signaling pathway activator.
Biological Activity
SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.
SJ000291942 Preparation Products And Raw materials
Raw materials
Preparation Products
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