Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester

Product Name: Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester
CAS No.: 1193111-39-5
Chemical Name: Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester
Synonyms: sulfo-SPDB;Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester;1-(2,5-Dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid
CBNumber: CB74657986
Molecular Formula: C13H14N2O7S3
Formula Weight: 406.45
MOL File: 1193111-39-5.mol

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Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Property

Density: 1.66±0.1 g/cm3(Predicted)
storage temp.: -80°C, protect from light, stored under nitrogen
solubility: Soluble in DMSO
pka: -0.08±0.50(Predicted)
form: Solid
color: Off-white to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0020918
Product name: sulfo-SPDB
Packaging: 5mg
Price: $350
Updated: 2021/12/16

Crysdot

Product number: CD35000128
Product name: 1-(2,5-dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonicacid
Purity: 95+%
Packaging: 1g
Price: $5072
Updated: 2021/12/16

Alichem

Product number: 1193111395
Product name: 1-(2,5-Dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonicacid
Packaging: 1g
Price: $5418.72
Updated: 2021/12/16

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Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Chemical Properties,Usage,Production

Uses

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: sulfo-SPDB 1193111-39-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: >95.00%
Supply Ability: 5mg
Release date: 2024-03-21

1193111-39-5, Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) esterRelated Search:

Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester

1-(2,5-Dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid

sulfo-SPDB

1193111-39-5

C13H14N2O7S3