2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID
- Product Name
- 2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID
- CAS No.
- 14736-50-6
- Chemical Name
- 2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID
- Synonyms
- Verazobone impurity 1;2-(2-Methoxy-2-oxoethyl);2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID;Benzeneacetic acid, 2-carboxy-, 1-methyl ester;Benzeneacetic acid, 2-carboxy-, a-Methyl ester
- CBNumber
- CB7466227
- Molecular Formula
- C10H10O4
- Formula Weight
- 194.18
- MOL File
- 14736-50-6.mol
2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID Property
- Melting point:
- 98-100 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
- Boiling point:
- 320.9±17.0 °C(Predicted)
- Density
- 1.254±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.69±0.36(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C10H10O4/c1-14-9(11)6-7-4-2-3-5-8(7)10(12)13/h2-5H,6H2,1H3,(H,12,13)
- InChIKey
- UKPMFGARCZOXDI-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=CC=C1CC(=O)OC
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M221830
- Product name
- 2-(2-Methoxy-2-Oxoethyl)BenzoicAcid
- Packaging
- 250mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- 7327AA
- Product name
- 2-(2-Methoxy-2-oxoethyl)benzoicacid
- Packaging
- 1g
- Price
- $251
- Updated
- 2021/12/16
- Product number
- 121300
- Product name
- 2-(2-Methoxy-2-oxoethyl)benzoicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $640
- Updated
- 2021/12/16
- Product number
- 121300
- Product name
- 2-(2-Methoxy-2-oxoethyl)benzoicacid
- Purity
- 97%
- Packaging
- 5g
- Price
- $1600
- Updated
- 2021/12/16
- Product number
- CHM0125764
- Product name
- 2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $3811.5
- Updated
- 2021/12/16
2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID Chemical Properties,Usage,Production
Synthesis
67-56-1
89-51-0
716-43-8
14736-50-6
The general procedure for the synthesis of methyl 2-(2-methoxy-2-oxoethyl)benzoate and 2-(2-methoxy-2-oxoethyl)benzoic acid from methanol and o-carboxybenzeneacetic acid was as follows: o-carboxybenzeneacetic acid (2.01 g, 10.0 mmol) was dissolved in methanol (10 mL), and the resultant solution was transferred to a syringe and mounted on a syringe pump. This methanol solution was pumped at a flow rate of 0.177 mL/min into a stainless steel column (4.0 mm ID x 50 mm length, 0.53 mL internal volume) filled with HO-SAS (334 mg). The column was immersed in an oil bath preheated to 110 °C and a back pressure regulator was connected to maintain the system pressure at 75 psi.The reaction effluent was discarded during the initial 10 min of the reaction, followed by the collection of the reaction mixture over 3 min and the addition of n-decane as an internal standard for the gas chromatographic analysis. The reaction effluent was continued to be collected in a glass flask for 30 min, after which the solvent was removed by rotary evaporation. The crude product was purified by silica gel fast column chromatography (eluent ratio hexane/ethyl acetate = 5/1) to give the final target product methyl 2-(2-methoxy-2-oxoethyl)benzoate (1.13 g, 99% yield).
References
[1] Journal of Chemical Research - Part S, 2000, # 6, p. 282 - 283
[2] Bulletin of the Chemical Society of Japan, 2017, vol. 90, # 5, p. 607 - 612
[3] Tetrahedron Letters, 2003, vol. 44, # 51, p. 9205 - 9208
[4] Journal of the Indian Chemical Society, 1987, vol. 64, # 1, p. 34 - 37
2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID manufacturers
- Product
- 2-(2-Methoxy-2-oxoEthyl)benzoic acid 14736-50-6
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17